SCHEMBL24359596

SCHEMBL24359596

Cn1ccnc1-c1cccc(-c2ccccc2-c2cc(C(C)(C)C)cc(C(C)(C)C)c2O)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.39
HTR2C P28335 2/20 0.39
HTR2A P28223 1/20 0.39
TSHR P16473 2/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
PKM P14618 1/20 0.37
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TGFBR1 P36897 1/20 0.35
CYP3A4 P08684 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
CYP1A2 P05177 1/20 0.33
MC4R P32245 1/20 0.32
BRD4 O60885 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29601177 1.00 HSP90AA1 (0.39) HSP90AA1HTR2CHTR2ATSHRKDM4E
SCHEMBL24359601 0.84 HSP90AA1 (0.50) HSP90AA1TSHRALDH1A1GAACYP3A4
SCHEMBL24359571 0.82 HSP90AA1 (0.44) HSP90AA1TSHRKDM4ELMNAGAA
SCHEMBL18890281 0.77 HSP90AA1 (0.56) HSP90AA1TSHRALDH1A1GAACYP3A4
SCHEMBL22320164 0.77 HSP90AA1 (0.49) HSP90AA1TSHRALDH1A1ALOX15HSD17B10
SCHEMBL22320167 0.75 HSP90AA1 (0.49) HSP90AA1TSHRCYP3A4CYP2C9CYP2C19
SCHEMBL22320298 0.75 CA2 (0.49) HSP90AA1TSHRALDH1A1GAAHSD17B10
SCHEMBL31036891 0.75 CA2 (0.49) HSP90AA1TSHRALDH1A1GAAHSD17B10
SCHEMBL25039125 0.74 HSP90AA1 (0.39) HSP90AA1TSHRALDH1A1GAACYP3A4
SCHEMBL22320315 0.73 SMN1; SMN2 (0.39) HSP90AA1TSHRALDH1A1HSD17B10CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312772-A1 Multidentate Lewis Base Catalysts and Methods for use Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-10-05 US disclosed
US-20230312772-A1 Multidentate Lewis Base Catalysts and Methods for use Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-10-05 US disclosed
WO-2022087121-A1 MULTIDENTATE LEWIS BASE CATALYSTS AND METHODS FOR USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-04-28 WO disclosed