SCHEMBL2436

SCHEMBL2436

Clc1cccc(CBr)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29353832 1.00
SCHEMBL5733314 1.00 PNMT (0.60)
SCHEMBL1001013 0.98 PNMT (0.58)
SCHEMBL11028540 0.98 PNMT (0.58)
SCHEMBL10876787 0.91 PNMT (0.52)
SCHEMBL27599728 0.89 PNMT (0.50)
SCHEMBL10987297 0.87 TAAR1 (0.55)
SCHEMBL20815578 0.84 CYP3A4 (0.46)
SCHEMBL25840770 0.83 TSHR (0.65)
SCHEMBL10879362 0.82 SLC6A4 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3003 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116375643-B Deaconitine derivative and preparation method and application thereof 中国人民解放军海军军医大学 2025-04-01 CN claimed
CN-119101052-A Matrine-triazole derivative and synthesis method thereof 吉林医药学院 2024-12-10 CN claimed
CN-118221691-B Methylenedioxybenzo [ b ] [1,4] diazepine [5,6-e ] triazinone derivative and pharmaceutically acceptable salt, preparation method and application thereof 常熟理工学院 2024-10-15 CN claimed
CN-117986413-A Catalyst component with high hydrogen regulation sensitivity, preparation method thereof, catalyst and application 中国石油化工股份有限公司 2024-05-07 CN claimed
CN-114773330-B Butylphthalide-oxa/thiadiazole compound and preparation method and application thereof 贵州医科大学 2024-03-15 CN claimed
CN-116715624-A Synthesis method of N-alkylated pyrithione compound 信阳师范学院 2023-09-08 CN claimed
CN-116375643-A Deaconitine derivative and preparation method and application thereof 中国人民解放军海军军医大学 2023-07-04 CN claimed
CN-112047928-B Isonicotinamide AChE-GSK3 double inhibitor and preparation method and application thereof 中国药科大学 2022-09-23 CN claimed
CN-114773330-A Butylphthalide-oxa/thiadiazole compound and preparation method and application thereof 贵州医科大学 2022-07-22 CN claimed
CN-112047928-A Isonicotinamide AChE-GSK3 double inhibitor and preparation method and application thereof 中国药科大学 2020-12-08 CN claimed
CN-110117252-A A kind of preparation process of 2-aminopyridine -6- methyl formate 南京博源医药科技有限公司 2019-08-13 CN claimed
US-20260146046-A1 BICYCLIC FERROPORTIN INHIBITORS VIFOR (INTERNATIONAL) AG (CH) 2026-05-28 US disclosed
WO-2026107371-A2 INDOLYL-PYRIDINONES AND RELATED COMPOUNDS AND THEIR USE IN THERAPY HOTSPOT THERAPEUTICS, INC. (US) 2026-05-21 WO disclosed
CN-122055361-A Fascin inhibitors 北京双鹤润创科技有限公司 2026-05-15 CN disclosed
EP-4741018-A2 SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2026-05-13 EP disclosed
US-4004016-A ANTIINFLAMMATORY E. R. SQUIBB & SONS, INC. (US) 1977-01-18 US disclosed
US-3970671-A XANTHENE, PRESSURE SENSITIVE KANZAKI PAPER MANUFACTURING CO., LTD. (JA) 1976-07-20 US disclosed
US-3953425-A Azepine indanyl and tetralin butyrophenones THE UPJOHN COMPANY (US) 1976-04-27 US disclosed
US-3947471-A CHROMOGENIC SUMITOMO CHEMICAL COMPANY, LTD. (JA) 1976-03-30 US disclosed
US-3932425-A CNS DEPRESSANT, BLOOD PRESSURE LOWERING THE UPJOHN COMPANY (US) 1976-01-13 US disclosed