Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.75 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.75 |
| ▸ | NOD1 | Q9Y239 | 13/20 | 0.56 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.52 |
| ▸ | FNTA | P49354 | 2/20 | 0.47 |
| ▸ | FNTB | P49356 | 2/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24359868 | 1.00 | PTGS1 (0.75) | PTGS1GSTK1NOD1GLO1FNTA | |
| SCHEMBL13259629 | 0.92 | PTGS1 (0.76) | PTGS1GSTK1NOD1GLO1FNTA | |
| SCHEMBL24668402 | 0.89 | PTGS1 (0.71) | PTGS1GSTK1NOD1GLO1FNTA | |
| SCHEMBL13747027 | 0.88 | NOD1 (0.58) | PTGS1GSTK1NOD1GLO1FOLH1 | |
| SCHEMBL928708 | 0.88 | PTGS1 (0.79) | PTGS1GSTK1NOD1GLO1FNTA | |
| SCHEMBL4408402 | 0.87 | PTGS1 (0.73) | PTGS1GSTK1NOD1GLO1FNTA | |
| SCHEMBL929035 | 0.87 | PTGS1 (0.72) | PTGS1GSTK1NOD1GLO1FNTA | |
| Glutathione SCHEMBL17629816 | 0.87 | PTGS1 (0.90) | PTGS1GSTK1NOD1GLO1FNTA | |
| Glutathione SCHEMBL28101167 | 0.87 | PTGS1 (0.90) | PTGS1GSTK1NOD1GLO1FNTA | |
| Propionamide SCHEMBL27610994 | 0.87 | PTGS1 (0.68) | PTGS1GSTK1NOD1GLO1FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022084738-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | Azura Ophthalmics Ltd. (IL) | 2022-04-28 | — | — | WO | disclosed |
| WO-2022084747-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | Azura Ophthalmics Ltd. (IL) | 2022-04-28 | — | — | WO | disclosed |
| WO-2022084739-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | Azura Ophthalmics Ltd. (IL) | 2022-04-28 | — | — | WO | disclosed |