Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24759311 | 0.77 | GRIN1 (0.35) | GRIN1GRIN2BRXRA | |
| SCHEMBL11679979 | 0.76 | RECQL (0.56) | HSP90AB1HTR2CHTR2BCXCR3POLB | |
| SCHEMBL24759309 | 0.73 | RXRA (0.44) | GRIN1GRIN2BRXRA | |
| SCHEMBL21652549 | 0.72 | MAPK13 (0.40) | HTR2CGRIN1GRIN2BRXRA | |
| SCHEMBL24852625 | 0.72 | HSP90AB1 (0.41) | HSP90AB1HTR2CHTR2BCXCR3POLB | |
| SCHEMBL23931342 | 0.70 | HTR2C (0.47) | HSP90AB1HTR2CHTR2BKDM4CMAPK1 | |
| SCHEMBL1437013 | 0.70 | SMARCA2 (0.44) | — | |
| SCHEMBL29528840 | 0.70 | SMARCA2 (0.44) | — | |
| SCHEMBL1569159 | 0.70 | CHEK2 (0.47) | HSP90AB1KDM4C | |
| SCHEMBL30271022 | 0.69 | L3MBTL1 (0.65) | HSP90AB1CXCR3MAPK1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780861-B2 | Phosphine reagents for azine fluoroalkylation | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2023-10-10 | — | — | US | disclosed |
| US-11780861-B2 | Phosphine reagents for azine fluoroalkylation | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2023-10-10 | — | — | US | disclosed |
| WO-2022087129-A9 | PHOSPHINE REAGENTS FOR AZINE FLUOROALKYLATION | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2022-05-27 | — | — | WO | disclosed |
| WO-2022087129-A1 | PHOSPHINE REAGENTS FOR AZINE FLUOROALKYLATION | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2022-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11780861-B2 | Phosphine reagents for azine fluoroalkylation | PTPN3, PHOSPHO1, SKIC3 | HSP90AB1 4848/4885HTR2C 835/4885HTR2B 2120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.