SCHEMBL2436355

SCHEMBL2436355

O=C(c1ccccc1)[S+]1CCCC1.O=C(c1ccccc1)[S+]1CCCC1.O=S(=O)([O-])C(F)(F)S(=O)(=O)[O-]

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.37
GPR3 P46089 1/20 0.35
CA2 P00918 4/20 0.32
CA12 O43570 4/20 0.32
CA1 P00915 4/20 0.32
CA9 Q16790 4/20 0.32
CA14 Q9ULX7 3/20 0.32
CA4 P22748 2/20 0.32
CA7 P43166 2/20 0.32
CA3 P07451 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA13 Q8N1Q1 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
LMNA P02545 3/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
FLT1 P17948 1/20 0.32
FLT4 P35916 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2437815 0.88 CES1 (0.35) CES1GPR3CA2CA12CA1
SCHEMBL2435742 0.88 CES1 (0.35) CES1GPR3CA2CA12CA1
SCHEMBL2441533 0.85 CES1 (0.33) CES1GPR3LMNA
SCHEMBL2434749 0.83 CES1 (0.31) CES1GPR3
SCHEMBL3740068 0.83 CES1 (0.31) CES1GPR3
SCHEMBL11926050 0.82 F2 (0.44) CES1CA2CA12CA1CA9
SCHEMBL2439082 0.81 LMNA (0.34) CES1CA2CA12CA1CA9
SCHEMBL2437510 0.80 LMNA (0.38) CES1LMNAL3MBTL1MEN1KMT2A
Bromide SCHEMBL3748538 0.80 F2 (0.43) CES1CA2CA12CA1CA9
SCHEMBL3829427 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2078028-B1 PHOTOACTIVE COMPOUNDS AZ ELECTRONIC MATERIALS USA (US) 2011-09-07 EP claimed