Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11926050 | 0.83 | F2 (0.44) | LMNASMN1; SMN2MAPTATMTSHR | |
| SCHEMBL2439082 | 0.83 | LMNA (0.34) | LMNASMN1; SMN2MAPTALDH1A1L3MBTL1 | |
| Bromide SCHEMBL3748538 | 0.81 | F2 (0.43) | LMNASMN1; SMN2MAPTATMTSHR | |
| SCHEMBL2436355 | 0.80 | CES1 (0.37) | LMNATSHRALDH1A1L3MBTL1MEN1 | |
| SCHEMBL2435742 | 0.78 | CES1 (0.35) | LMNAL3MBTL1MEN1KMT2AFLT1 | |
| SCHEMBL2437815 | 0.78 | CES1 (0.35) | LMNAL3MBTL1MEN1KMT2AFLT1 | |
| SCHEMBL2434749 | 0.73 | CES1 (0.31) | CES1 | |
| SCHEMBL3740068 | 0.73 | CES1 (0.31) | CES1 | |
| SCHEMBL11926051 | 0.69 | ALDH1A1 (0.48) | LMNASMN1; SMN2NPSR1MAPTATM | |
| SCHEMBL10424358 | 0.66 | TSSK1B (0.46) | LMNASMN1; SMN2NPSR1MAPTXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078028-B1 | PHOTOACTIVE COMPOUNDS | AZ ELECTRONIC MATERIALS USA (US) | 2011-09-07 | — | — | EP | claimed |