Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CECR2 | Q9BXF3 | 20/20 | 0.70 |
| ▸ | TAF1 | P21675 | 17/20 | 0.70 |
| ▸ | BRD9 | Q9H8M2 | 17/20 | 0.70 |
| ▸ | BRD4 | O60885 | 16/20 | 0.70 |
| ▸ | TAF11 | Q15544 | 1/20 | 0.46 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17758434 | 0.82 | TAF1 (1.00) | CECR2TAF1BRD9BRD4TAF11 | |
| SCHEMBL17749793 | 0.75 | TAF1 (1.00) | CECR2TAF1BRD9BRD4TAF11 | |
| SCHEMBL30373817 | 0.73 | TAF1 (0.81) | CECR2TAF1BRD9BRD4TAF11 | |
| SCHEMBL19657115 | 0.72 | BRD4 (0.50) | CECR2TAF1BRD9BRD4 | |
| SCHEMBL30073356 | 0.70 | CECR2 (0.55) | CECR2TAF1BRD9BRD4TAF11 | |
| SCHEMBL17758548 | 0.70 | CECR2 (0.55) | CECR2TAF1BRD9BRD4TAF11 | |
| SCHEMBL17749882 | 0.68 | TAF1 (1.00) | CECR2TAF1BRD9BRD4TAF11 | |
| SCHEMBL19651852 | 0.67 | BRD4 (0.48) | CECR2TAF1BRD9BRD4 | |
| SCHEMBL19657251 | 0.67 | CECR2 (0.73) | CECR2TAF1BRD9BRD4 | |
| SCHEMBL24363697 | 0.66 | BRD4 (0.47) | CECR2TAF1BRD9BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218375-B1 | SUBSTITUTED PYRROLOPYRDINES AS INHIBITORS OF BROMODOMAIN | GENENTECH INC (US) | 2022-04-27 | — | — | EP | disclosed |