SCHEMBL2436397

SCHEMBL2436397

Cc1ccc2c(c1)-c1ccccc1[PH](=O)O2

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.42
CYP19A1 P11511 2/20 0.36
KDM4E B2RXH2 4/20 0.33
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
GAA P10253 1/20 0.33
ROS1 P08922 1/20 0.33
CDK5 Q00535 1/20 0.33
ACVR1 Q04771 1/20 0.33
LRRK2 Q5S007 1/20 0.33
MAOB P27338 4/20 0.32
MAOA P21397 2/20 0.32
HTT P42858 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2439665 0.87 ELANE (0.42) ELANECYP19A1ALDH1A1LMNAMAOB
SCHEMBL2438109 0.83 ELANE (0.42) ELANECYP19A1KDM4ELMNAMAOB
SCHEMBL29363087 0.80 HSP90AA1 (0.35) KDM4EATM
SCHEMBL30781 0.80 HSP90AA1 (0.35) KDM4EATM
SCHEMBL29395467 0.80 HSP90AA1 (0.35) KDM4EATM
SCHEMBL2435971 0.80 NR1H3 (0.36) HSD17B10LMNAMAPT
SCHEMBL2435389 0.80 SMN1; SMN2 (0.46) ALDH1A1LMNAMAPTATM
SCHEMBL2433717 0.79 MEN1 (0.42) KDM4EALDH1A1LMNAMAPTGAA
SCHEMBL11243703 0.78 S100A4 (0.46) KDM4EALDH1A1MAPTGAAMAOB
SCHEMBL31183036 0.78 HSP90AA1 (0.34) KDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592071-B2 Laminated porous film and separator for battery MITSUBISHI PLASTICS, INC. (JP) 2013-11-26 US disclosed
US-20110212358-A1 LAMINATED POROUS FILM AND SEPARATOR FOR BATTERY MITSUBISHI PLASTICS, INC. (JP) 2011-09-01 US disclosed
EP-0790262-B1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORP (JP) 2000-05-10 EP disclosed
US-6005034-A POLYMER MELTS OF ETHYLENE-PROPYLENE COPOLYMERS CHISSO CORPOATION (JP) 1999-12-21 US disclosed
EP-0790262-A1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORPORATION (JP) 1997-08-20 EP disclosed
US-4086206-A FLAME RETARDANTS, DEHYDROCONDENSATION SANKO KAIHATSU KAGAKU KENKYOSHO (JA) 1978-04-25 US disclosed