SCHEMBL2439665

SCHEMBL2439665

Cc1ccc2c(c1)O[PH](=O)c1ccccc1-2

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.42
MAOB P27338 10/20 0.37
MAOA P21397 3/20 0.37
CYP19A1 P11511 2/20 0.37
LMNA P02545 1/20 0.35
CSNK1G1 Q9HCP0 1/20 0.34
PDK2 Q15119 1/20 0.31
ALDH1A1 P00352 1/20 0.31
ALDH2 P05091 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2438109 0.87 ELANE (0.42) ELANEMAOBMAOACYP19A1LMNA
SCHEMBL2436397 0.87 ELANE (0.42) ELANEMAOBMAOACYP19A1LMNA
SCHEMBL30781 0.80 HSP90AA1 (0.35)
SCHEMBL29395467 0.80 HSP90AA1 (0.35)
SCHEMBL29363087 0.80 HSP90AA1 (0.35)
Bromide SCHEMBL28619414 0.78 HSP90AA1 (0.34)
SCHEMBL30598814 0.78 HSP90AA1 (0.34)
SCHEMBL31183036 0.78 HSP90AA1 (0.34)
SCHEMBL28437933 0.78 HSP90AA1 (0.34)
Phosphine SCHEMBL28051578 0.78 HSP90AA1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10329405-B2 Modified polymer composition and stabilizer mixture for making the same FDC, LEES CO., LTD. (TW) 2019-06-25 US disclosed
US-8592071-B2 Laminated porous film and separator for battery MITSUBISHI PLASTICS, INC. (JP) 2013-11-26 US disclosed
US-20110212358-A1 LAMINATED POROUS FILM AND SEPARATOR FOR BATTERY MITSUBISHI PLASTICS, INC. (JP) 2011-09-01 US disclosed
EP-0790262-B1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORP (JP) 2000-05-10 EP disclosed
US-6005034-A POLYMER MELTS OF ETHYLENE-PROPYLENE COPOLYMERS CHISSO CORPOATION (JP) 1999-12-21 US disclosed
EP-0790262-A1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORPORATION (JP) 1997-08-20 EP disclosed