SCHEMBL2436427

SCHEMBL2436427

CCC[C@H]1CC[C@H](c2ccccc2C2(O)C=CC(C(=O)O)C=C2)CC1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.39
MAPT P10636 2/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
OPRL1 P41146 3/20 0.34
MEN1 O00255 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD11B1 P28845 1/20 0.32
CYSLTR2 Q9NS75 1/20 0.32
CYSLTR1 Q9Y271 1/20 0.32
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9517894 0.82 CYP2C9 (0.37) CYP2C9MAPTALDH1A1LMNAOPRL1
SCHEMBL9514174 0.76 MAPT (0.32) CYP2C9MAPTALDH1A1LMNAOPRL1
SCHEMBL9516779 0.75 CYSLTR2 (0.35) CYP2C9MAPTMEN1KMT2ACYSLTR2
SCHEMBL8045323 0.75 CYP2C9 (0.34) CYP2C9MAPTALDH1A1LMNAOPRL1
SCHEMBL7510560 0.75 CYP2C9 (0.34) CYP2C9MAPTALDH1A1LMNAOPRL1
SCHEMBL9513977 0.75 CYP2C9 (0.36) CYP2C9MAPTALDH1A1LMNAOPRL1
SCHEMBL9516412 0.75 CYSLTR2 (0.36) ALDH1A1CYSLTR2CYSLTR1
SCHEMBL9515658 0.75 CYSLTR2 (0.36) ALDH1A1CYSLTR2CYSLTR1
SCHEMBL9518034 0.75 CYSLTR2 (0.36) ALDH1A1CYSLTR2CYSLTR1
SCHEMBL9514070 0.75 CYSLTR2 (0.36) ALDH1A1CYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3673521-B1 DIELECTRIC LAYER COMPRISING COPOLYMER WITH MESOGENIC UNITS PPG IND OHIO INC (US) 2023-08-09 EP disclosed
US-11525087-B2 Dielectric devices and methods of fabrication PPG INDUSTRIES OHIO, INC. (US) 2022-12-13 US disclosed
US-20200263092-A1 DIELECTRIC DEVICES AND METHODS OF FABRICATION PPG INDUSTRIES OHIO, INC. 2020-08-20 US disclosed
EP-3673521-A1 DIELECTRIC LAYER COMPRISING COPOLYMER WITH MESOGENIC UNITS PPG Industries Ohio, Inc. (US) 2020-07-01 EP disclosed
US-10619099-B2 Dielectric devices and methods of fabrication PPG INDUSTRIES OHIO, INC. (US) 2020-04-14 US disclosed
WO-2019040934-A1 DIELECTRIC LAYER COMPRISING COPOLYMER WITH MESOGENIC UNITS PPG INDUSTRIES OHIO, INC. (US) 2019-02-28 WO disclosed
EP-2686401-B9 MESOGEN-CONTAINING COMPOUNDS TRANSITIONS OPTICAL INC (US) 2017-05-31 EP disclosed
EP-2686401-B1 MESOGEN-CONTAINING COMPOUNDS TRANSITIONS OPTICAL INC (US) 2016-11-23 EP disclosed
EP-2686401-A1 MESOGEN-CONTAINING COMPOUNDS Transitions Optical, Inc. (US) 2014-01-22 EP disclosed
US-8628685-B2 Mesogen-containing compounds TRANSITIONS OPTICAL, INC (US) 2014-01-14 US disclosed
WO-2012128944-A1 MESOGEN-CONTAINING COMPOUNDS TRANSITIONS OPTICAL, INC. (US) 2012-09-27 WO disclosed
US-20110216273-A1 MESOGEN-CONTAINING COMPOUNDS TRANSITIONS OPTICAL, INC. (US) 2011-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110216273-A1 MESOGEN-CONTAINING COMPOUNDS BMP2, MYOC, RARG CYP2C9 2756/4885MAPT 2276/4885ALDH1A1 724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.