SCHEMBL24364714

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24366504	0.84	HSD11B1 (0.50)	ALDH1A1MAPTSMN1; SMN2LMNAKMT2A
	SCHEMBL11859410	0.83	TDP1 (0.48)	NPC1L3MBTL1TDP1GLAALDH1A1
	SCHEMBL11859406	0.83	TDP1 (0.48)	NPC1L3MBTL1TDP1GLAALDH1A1
	SCHEMBL7945432	0.81	TDP1 (0.53)	NPC1L3MBTL1TDP1GLAALDH1A1
	SCHEMBL7933720	0.81	TDP1 (0.53)	NPC1L3MBTL1TDP1GLAALDH1A1
	Maleic Acid SCHEMBL11865993	0.79	HDAC3 (0.50)	NPC1L3MBTL1TDP1GLAALDH1A1
	Maleic Acid SCHEMBL11866000	0.79	HDAC3 (0.50)	NPC1L3MBTL1TDP1GLAALDH1A1
	SCHEMBL31145160	0.78	PADI4 (0.38)	NPC1MAPTHDAC3HDAC1HDAC6
	SCHEMBL24365575	0.78	PADI4 (0.38)	NPC1MAPTHDAC3HDAC1HDAC6
	SCHEMBL29323985	0.78	PTGS2 (0.45)	ALDH1A1CYP1A2HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.