SCHEMBL24366151

SCHEMBL24366151

CNCC(=O)N[C@H](C=O)Cc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 7/20 0.57
CTSB P07858 5/20 0.52
ACE P12821 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21653923 1.00 CAPN1 (0.57) CAPN1CTSBACE
SCHEMBL16153848 0.84 CTSB (0.57) CAPN1CTSBACE
SCHEMBL16566002 0.83 MME (0.58) CAPN1CTSBACE
SCHEMBL16485210 0.81 CTSC (0.57) CAPN1CTSBACE
SCHEMBL11863658 0.81 MMP2 (0.54) CAPN1CTSBACE
SCHEMBL19365045 0.81 MMP2 (0.54) CAPN1CTSBACE
SCHEMBL27377816 0.81 HDAC3 (0.41) CAPN1CTSB
SCHEMBL20881309 0.81 CTSB (0.49) CAPN1CTSB
SCHEMBL24760199 0.81 CTSB (0.49) CAPN1CTSBACE
SCHEMBL2269431 0.81 CAPN1 (0.58) CAPN1CTSBACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022084417-A1 CONJUGATED TLR7 AND NOD2 AGONISTS UNIVERZA V LJUBLJANI (SI) 2022-04-28 WO disclosed