Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1365239 | 0.74 | NR4A2 (0.39) | NR4A2DHODH | |
| SCHEMBL24365752 | 0.72 | NAMPT (0.35) | — | |
| SCHEMBL1884974 | 0.66 | NR4A2 (0.43) | NR4A2DHODH | |
| SCHEMBL27937978 | 0.66 | KDM4E (0.43) | — | |
| SCHEMBL31145148 | 0.65 | CHRNB4 (0.41) | NR4A2DHODH | |
| SCHEMBL12637430 | 0.64 | NPC1 (0.40) | NR4A2DHODH | |
| SCHEMBL27527824 | 0.64 | TOP2A (0.42) | NR4A2DHODH | |
| SCHEMBL12637425 | 0.64 | NR4A2 (0.42) | NR4A2DHODH | |
| SCHEMBL26267083 | 0.64 | NAMPT (0.39) | NR4A2DHODH | |
| SCHEMBL24367660 | 0.63 | JAK2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228478-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2024-07-11 | — | — | US | disclosed |
| US-20220127256-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127256-A1 | COMPOUNDS AND METHODS OF USE | F12, C1R, ABCG2 | NR4A2 2461/4885DHODH 1997/4885 |
| US-20240228478-A1 | COMPOUNDS AND METHODS OF USE | F12, C1R, ABCG2 | NR4A2 2461/4885DHODH 1997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.