Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | DPP4 | P27487 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16291133 | 0.90 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL3545 | 0.90 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL30398774 | 0.87 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1KDM4EMAPTMEN1 | |
| Bromide SCHEMBL29519314 | 0.87 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL29776515 | 0.87 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1KDM4EMAPTMEN1 | |
| Ammonia Solution, Strong SCHEMBL34467257 | 0.87 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1KDM4EMAPTMEN1 | |
| Benzene SCHEMBL28420098 | 0.87 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1KDM4EMAPTMEN1 | |
| Bromide SCHEMBL30467088 | 0.87 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1KDM4EMAPTMEN1 | |
| Hydrogen Sulfide SCHEMBL22588115 | 0.87 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1KDM4EMAPTMEN1 | |
| Fluoride SCHEMBL491501 | 0.87 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1KDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853424-B2 | Protein cross-linking inhibitor | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2014-10-07 | — | — | US | disclosed |
| US-20110212919-A1 | PROTEIN CROSS-LINKING INHIBITOR | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212919-A1 | PROTEIN CROSS-LINKING INHIBITOR | BAZ2B, PRMT1, BRIX1 | L3MBTL1 1358/4885ALDH1A1 4540/4885KDM4E 1022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.