SCHEMBL2436799

SCHEMBL2436799

O=C(O)CC12CC3(CC(=O)O)CC(CC(=O)O)(C1)CC(CC(=O)O)(C2)C3

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM1 Q13255 1/20 0.60
POLB P06746 1/20 0.45
CYP2C19 P33261 1/20 0.40
LMNA P02545 3/20 0.37
ALDH1A1 P00352 2/20 0.37
TSHR P16473 2/20 0.37
CYP1A2 P05177 2/20 0.37
USP2 O75604 1/20 0.37
BLM P54132 1/20 0.37
CACNA2D1 P54289 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GABRA5 P31644 1/20 0.34
GABRB2 P47870 1/20 0.34
LDHA P00338 1/20 0.33
SRR Q9GZT4 1/20 0.33
ALKBH5 Q6P6C2 1/20 0.33
SUCNR1 Q9BXA5 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
HSD11B1 P28845 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29772200 0.89 GRM1 (0.52) GRM1POLBCYP2C19LMNAALDH1A1
SCHEMBL7530245 0.84 GRM1 (0.48) GRM1POLBCYP2C19ALDH1A1TSHR
SCHEMBL25251941 0.83 GRM1 (0.47) GRM1POLBCYP2C19LMNAALDH1A1
SCHEMBL17586294 0.83 GRM1 (0.47) GRM1POLBCYP2C19LMNAALDH1A1
SCHEMBL12858244 0.81 GRM1 (0.45) GRM1POLBCYP2C19ALDH1A1TSHR
SCHEMBL13687267 0.79 GRM1 (0.44) GRM1POLBCYP2C19LMNAALDH1A1
SCHEMBL30559862 0.79 GRM1 (0.48) GRM1POLBCYP2C19LMNAALDH1A1
SCHEMBL25127021 0.77 GRM1 (0.42) GRM1POLBCYP2C19ALDH1A1TSHR
Ammonia Solution, Strong SCHEMBL23540220 0.77 GRM1 (0.47) GRM1POLBCYP2C19LMNAALDH1A1
SCHEMBL1058665 0.77 POLB (0.75) POLBLMNAALDH1A1TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8022151-B2 Adamantane derivative, method for producing the same, resin composition containing the adamantane derivative and use thereof IDEMITSU KOSAN CO., LTD. (JP) 2011-09-20 US disclosed
US-20100093947-A1 ADAMANTANE DERIVATIVE, METHOD FOR PRODUCING THE SAME, RESIN COMPOSITION CONTAINING THE ADAMANTANE DERIVATIVE AND USE THEREOF IDEMITSU KOSAN CO., LTD. (JP) 2010-04-15 US disclosed