Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12858244 | 0.98 | GRM1 (0.45) | GRM1PKMPOLBGABRA5GABRB2 | |
| SCHEMBL17586294 | 0.95 | GRM1 (0.47) | GRM1PKMPOLBGABRA5GABRB2 | |
| SCHEMBL11107723 | 0.86 | GRM1 (0.38) | GRM1PKMPOLBGABRA5GABRB2 | |
| SCHEMBL2436799 | 0.84 | GRM1 (0.60) | GRM1POLBGABRA5GABRB2ALDH1A1 | |
| SCHEMBL14571709 | 0.78 | GRM1 (0.50) | GRM1POLBGABRA5GABRB2ALDH1A1 | |
| SCHEMBL1786642 | 0.77 | MEN1 (0.53) | POLBALDH1A1TSHRCYP2C19 | |
| SCHEMBL5145929 | 0.76 | PKM (0.50) | GRM1PKMALDH1A1RAB9ATSHR | |
| SCHEMBL4982669 | 0.76 | PKM (0.39) | PKMALDH1A1RAB9ATSHRHSD17B10 | |
| SCHEMBL29772200 | 0.75 | GRM1 (0.52) | GRM1POLBGABRA5GABRB2ALDH1A1 | |
| SCHEMBL25070961 | 0.73 | CYP2C19 (0.38) | GRM1POLBGABRA5GABRB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028719-A1 | SCREENING METHODS FOR AMYLOID BETA MODULATORS | WARATAH PHARMACEUTICALS INC. (CA) | 2011-02-03 | — | — | US | disclosed |
| US-20110028719-A1 | SCREENING METHODS FOR AMYLOID BETA MODULATORS | WARATAH PHARMACEUTICALS INC. (CA) | 2011-02-03 | — | — | US | disclosed |
| US-6455666-B1 | POLYMERIZATION OF ADAMANTANE DICARBOXY AND DIHYDROXY DERIVATIVES | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-09-24 | — | — | US | disclosed |
| US-20020042496-A1 | Novel polyesters and production process thereof | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-04-11 | — | — | US | disclosed |
| EP-0053621-B1 | UNSATURATED ESTERS OF ADAMANTANE CONTAINING DIOLS AND THERMO-RESISTANT CROSS-LINKED POLYMERS THEREFROM | BATTELLE MEMORIAL INSTITUTE (CH) | 1984-07-25 | — | — | EP | disclosed |
| EP-0053621-A1 | UNSATURATED ESTERS OF ADAMANTANE CONTAINING DIOLS AND THERMO-RESISTANT CROSS-LINKED POLYMERS THEREFROM. | BATTELLE MEMORIAL INSTITUTE (CH) | 1982-06-16 | — | — | EP | disclosed |
| US-4332964-A | Unsaturated esters of adamantane containing diols and thermo-resistant cross-linked polymers therefrom | BATTELLE DEVELOPMENT CORPORATION (US) | 1982-06-01 | — | — | US | disclosed |
| WO-1981003657-A1 | UNSATURATED ESTERS OF ADAMANTANE CONTAINING DIOLS AND THERMO-RESISTANT CROSS-LINKED POLYMERS THEREFROM | BATTELLE MEMORIAL INSTITUTE (CH) | 1981-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028719-A1 | SCREENING METHODS FOR AMYLOID BETA MODULATORS | APP, BACE1, IAPP | GRM1 2470/4885PKM 3506/4885POLB 4264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.