Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2436799 | 0.83 | GRM1 (0.60) | GRM1POLBCYP2C19TSHRALDH1A1 | |
| SCHEMBL30932376 | 0.80 | OR51E2 (0.32) | GRM1 | |
| SCHEMBL30281342 | 0.77 | GRM1 (0.32) | GRM1 | |
| SCHEMBL17586294 | 0.74 | GRM1 (0.47) | GRM1POLBCYP2C19TSHRALDH1A1 | |
| SCHEMBL29772200 | 0.74 | GRM1 (0.52) | GRM1POLBCYP2C19TSHRALDH1A1 | |
| SCHEMBL17582384 | 0.73 | GRM1 (0.42) | GRM1POLBCYP2C19 | |
| SCHEMBL14571709 | 0.72 | GRM1 (0.50) | GRM1POLBCYP2C19TSHRALDH1A1 | |
| SCHEMBL12858244 | 0.72 | GRM1 (0.45) | GRM1POLBCYP2C19TSHRALDH1A1 | |
| SCHEMBL7530245 | 0.70 | GRM1 (0.48) | GRM1POLBCYP2C19TSHRALDH1A1 | |
| SCHEMBL30559862 | 0.70 | GRM1 (0.48) | GRM1POLBCYP2C19TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720035-A1 | LIPID COMPOUNDS, COMPOSITIONS, AND USES THEREOF | LIBERATE BIO, INC. (US) | 2026-04-08 | — | — | EP | disclosed |
| CN-119948023-A | Regulator containing piperidine polycyclic derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2025-05-06 | — | — | CN | disclosed |
| WO-2024249525-A1 | LIPID COMPOUNDS, COMPOSITIONS, AND USES THEREOF | LIBERATE BIO, INC. (US) | 2024-12-05 | — | — | WO | disclosed |
| EP-4408530-A1 | BENZIMIDAZOLES AS MODULATORS OF IL-17 | Janssen Pharmaceutica NV (BE) | 2024-08-07 | — | — | EP | disclosed |
| CN-118451079-A | Benzopiperidine derivative modulators, methods of preparation and uses thereof | 上海翰森生物医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |
| WO-2023125935-A1 | BENZOPYRIDINE DERIVATIVE REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |
| WO-2023049888-A1 | BENZIMIDAZOLES AS MODULATORS OF IL-17 | JANSSEN PHARMACEUTICA NV (BE) | 2023-03-30 | — | — | WO | disclosed |