SCHEMBL24368205

SCHEMBL24368205

CN1CCCC1C(=O)NCCS

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
NPSR1 Q6W5P4 1/20 0.41
POLB P06746 1/20 0.38
TSHR P16473 1/20 0.38
FKBP1A P62942 4/20 0.36
ACE P12821 3/20 0.36
LMNA P02545 2/20 0.36
HSD17B10 Q99714 2/20 0.36
CYP2C19 P33261 1/20 0.36
KDM4E B2RXH2 1/20 0.36
F2 P00734 1/20 0.36
REN P00797 1/20 0.36
LTA4H P09960 1/20 0.36
MAPT P10636 1/20 0.36
PEPD P12955 1/20 0.36
ALOX15 P16050 1/20 0.36
PTGS1 P23219 1/20 0.36
HTR2A P28223 1/20 0.36
PTGS2 P35354 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4577535 0.85 CYP3A4 (0.47) CYP3A4CYP2D6NPSR1POLBTSHR
SCHEMBL26343602 0.85 NPSR1 (0.48) CYP3A4CYP2D6NPSR1POLBTSHR
SCHEMBL4579409 0.85 CYP3A4 (0.47) CYP3A4CYP2D6NPSR1POLBTSHR
SCHEMBL4577528 0.85 CYP3A4 (0.47) CYP3A4CYP2D6NPSR1POLBTSHR
SCHEMBL5737180 0.85 CYP3A4 (0.47) CYP3A4CYP2D6NPSR1POLBTSHR
SCHEMBL12733389 0.85 NPSR1 (0.48) CYP3A4CYP2D6NPSR1POLBTSHR
SCHEMBL14271686 0.84 L3MBTL1 (0.46) CYP3A4CYP2D6NPSR1POLBTSHR
SCHEMBL12733444 0.83 CYP3A4 (0.46) CYP3A4CYP2D6NPSR1POLBTSHR
SCHEMBL13997594 0.83 CYP3A4 (0.46) CYP3A4CYP2D6NPSR1POLBTSHR
SCHEMBL21696640 0.82 NPSR1 (0.59) CYP3A4CYP2D6NPSR1POLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022082312-A1 NOVEL CXCR4-TARGETING COMPOUNDS PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2022-04-28 WO disclosed