Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.56 |
| ▸ | KLK7 | P49862 | 12/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 10/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17104764 | 0.88 | BCHE (0.46) | BCHEKLK7KLK5 | |
| SCHEMBL21574397 | 0.86 | BCHE (0.65) | BCHEKLK7KLK5PSEN1PSEN2 | |
| SCHEMBL4752349 | 0.86 | BCHE (0.65) | BCHEKLK7KLK5PSEN1PSEN2 | |
| SCHEMBL12310121 | 0.83 | BCHE (0.49) | BCHEKLK7KLK5 | |
| SCHEMBL2440031 | 0.83 | BCHE (0.49) | BCHEKLK7KLK5 | |
| SCHEMBL22527529 | 0.82 | AR (0.44) | BCHEPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL22527530 | 0.82 | AR (0.44) | BCHEPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL17104794 | 0.82 | BCHE (0.58) | BCHEKLK7KLK5PSEN1PSEN2 | |
| SCHEMBL22527528 | 0.82 | AR (0.44) | BCHEPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL22692847 | 0.81 | PSEN1 (0.41) | BCHEKLK7KLK5PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10377765-B2 | Polyester ethers derived from asymmetrical monomers based upon bisanhydrohexitols | NEW JERSEY INSTITUTE OF TECHNOLOGY (US) | 2019-08-13 | — | — | US | disclosed |
| US-20160369046-A1 | NEW POLYESTER ETHERS DERIVED FROM ASYMMETRICAL MONOMERS BASED UPON BISANHYDROHEXITOLS | NEW JERSEY INSTITUTE OF TECHNOLOGY | 2016-12-22 | — | — | US | disclosed |
| US-9447230-B2 | Polyester ethers derived from asymmetrical monomers based upon bisanydrohexitols | NEW JERSEY INSTITUTE OF TECHNOLOGY (US) | 2016-09-20 | — | — | US | disclosed |
| EP-2548203-A1 | NEW POLYESTER ETHERS DERIVED FROM ASYMMETRICAL MONOMERS BASED UPON BISANHYDROHEXITOLS | New Jersey Institute of Technology (US) | 2013-01-23 | — | — | EP | disclosed |
| US-20110257346-A1 | Polyester Ethers Derived From Asymmetrical Monomers Based Upon Bisanydrohexitols | IOWA CORN PROMOTION BOARD (US) | 2011-10-20 | — | — | US | disclosed |
| WO-2011116270-A1 | NEW POLYESTER ETHERS DERIVED FROM ASYMMETRICAL MONOMERS BASED UPON BISANHYDROHEXITOLS | NEW JERSEY INSTITUTE OF TECHNOLOGY (US) | 2011-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160369046-A1 | NEW POLYESTER ETHERS DERIVED FROM ASYMMETRICAL MONOMERS BASED UPON BISANHYDROHEXITOLS | GNE, DCXR, DERA | BCHE 1882/4885KLK7 2761/4885KLK5 4093/4885 |
| US-10377765-B2 | Polyester ethers derived from asymmetrical monomers based upon bisanhydrohexitols | DCXR, CBR1, AKR1C4 | BCHE 1752/4885KLK7 3676/4885KLK5 4307/4885 |
| US-20110257346-A1 | Polyester Ethers Derived From Asymmetrical Monomers Based Upon Bisanydrohexitols | GNE, FHIT, DCXR | BCHE 1868/4885KLK7 2837/4885KLK5 4296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.