Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | FHIT | P49789 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | IRS1 | P35568 | 1/20 | 0.39 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4315953 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL299130 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL12635484 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL283280 | 0.78 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL15945408 | 0.78 | GAA (0.50) | ALDH1A1MAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL4080719 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL281865 | 0.78 | MAPT (0.43) | ALDH1A1MAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL20888432 | 0.77 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL13477788 | 0.76 | GAA (0.44) | ALDH1A1MAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL2113638 | 0.75 | ALDH1A1 (0.45) | ALDH1A1MAPTHPGDSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087634-A1 | CTPS1 INHIBITORS AND USES THEREOF | NIMBUS CLOTHO, INC. (US) | 2022-04-28 | — | — | WO | disclosed |