SCHEMBL24370068

SCHEMBL24370068

N#Cc1ccc(-n2c3ccccc3c3cc(-c4ccc(-n5c6ccccc6c6ccccc65)c(-c5ccccc5)c4)ccc32)c(-c2ccc(C#N)cc2C(F)(F)F)c1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.35
PDK2 Q15119 2/20 0.34
PTGER4 P35408 1/20 0.33
AR P10275 6/20 0.32
GABRA1 P14867 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
GABRA2 P47869 1/20 0.32
METAP2 P50579 1/20 0.32
S1PR1 P21453 2/20 0.32
S1PR3 Q99500 2/20 0.32
ACP1 P24666 1/20 0.32
TRPV4 Q9HBA0 1/20 0.32
CYP19A1 P11511 1/20 0.31
PTGDR2 Q9Y5Y4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24369956 0.97 KIF11 (0.37) KIF11PDK2PTGER4ARGABRA1
SCHEMBL22984999 0.94 KIF11 (0.38) KIF11PDK2PTGER4ARGABRA1
SCHEMBL24370162 0.94 AR (0.36) KIF11PDK2PTGER4ARACP1
SCHEMBL24370070 0.92 KIF11 (0.36) KIF11PDK2PTGER4ARTRPV4
SCHEMBL22985252 0.91 PDK2 (0.40) KIF11PDK2PTGER4ARACP1
SCHEMBL22985410 0.91 KIF11 (0.41) KIF11PDK2PTGER4ARTRPV4
SCHEMBL24370446 0.91 AR (0.37) KIF11PDK2PTGER4AR
SCHEMBL22984983 0.91 KIF11 (0.40) KIF11PDK2ARGABRA1GABRG2
SCHEMBL22985582 0.90 KIF11 (0.36) KIF11PDK2PTGER4ARS1PR1
SCHEMBL22985608 0.89 AR (0.39) KIF11PDK2PTGER4ARTRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220131080-A1 CARBAZOLE DERIVATES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2022-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220131080-A1 CARBAZOLE DERIVATES FOR USE IN OPTOELECTRONIC DEVICES SIK3, ORAI3, HIPK3 KIF11 3200/4885PDK2 1675/4885PTGER4 1355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.