SCHEMBL24370165

SCHEMBL24370165

N#Cc1ccc(-n2c3ccccc3c3cc(-c4ccccc4-n4c5ccccc5c5ccccc54)ccc32)c(-c2ccc(C#N)cc2C(F)(F)F)c1

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
AR P10275 10/20 0.38
PGR P06401 2/20 0.36
PDK2 Q15119 3/20 0.34
KIF11 P52732 1/20 0.34
PTGER4 P35408 1/20 0.34
ACP1 P24666 1/20 0.33
TRPV4 Q9HBA0 1/20 0.33
NSD2 O96028 1/20 0.32
ENPP1 P22413 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24370162 0.96 AR (0.36) ARPGRPDK2KIF11PTGER4
SCHEMBL24370445 0.92 KIF11 (0.38) ARPGRPDK2KIF11PTGER4
SCHEMBL22985060 0.92 AR (0.38) ARPGRPDK2KIF11PTGER4
SCHEMBL24370070 0.92 KIF11 (0.36) ARPGRPDK2KIF11PTGER4
SCHEMBL22985608 0.91 AR (0.39) ARPGRPDK2KIF11PTGER4
SCHEMBL24370163 0.91 KIF11 (0.36) ARPGRKIF11PTGER4
SCHEMBL22985323 0.91 KIF11 (0.39) ARPGRPDK2KIF11PTGER4
SCHEMBL24369956 0.91 KIF11 (0.37) ARPGRPDK2KIF11PTGER4
SCHEMBL24370446 0.91 AR (0.37) ARPGRPDK2KIF11PTGER4
SCHEMBL22985410 0.91 KIF11 (0.41) ARPGRPDK2KIF11PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220131080-A1 CARBAZOLE DERIVATES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2022-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220131080-A1 CARBAZOLE DERIVATES FOR USE IN OPTOELECTRONIC DEVICES SIK3, ORAI3, HIPK3 AR 4858/4885PGR 4682/4885PDK2 1675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.