SCHEMBL24372289

SCHEMBL24372289

CCCCCCCCCOCCCCCCCN(CCCCCCCC(=O)OC(CCCCCCCC)CCCCCCCC)C[C@@H](C)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
MAPK1 P28482 3/20 0.46
LMNA P02545 4/20 0.44
ALDH1A1 P00352 1/20 0.44
PRKCA P17252 1/20 0.41
PRKCE Q02156 1/20 0.41
PRKCQ Q04759 1/20 0.41
PRKCD Q05655 1/20 0.41
RECQL P46063 1/20 0.40
CYP1A2 P05177 2/20 0.39
TP53 P04637 2/20 0.39
TSHR P16473 2/20 0.39
MEN1 O00255 1/20 0.39
GMNN O75496 1/20 0.39
HSP90AA1 P07900 1/20 0.39
BLM P54132 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
NR1H4 Q96RI1 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22645879 0.92 LMNA (0.49) MAPTMAPK1LMNAALDH1A1PRKCA
SCHEMBL18665374 0.92 LMNA (0.49) MAPTMAPK1LMNAALDH1A1PRKCA
SCHEMBL31065291 0.92 LMNA (0.49) MAPTMAPK1LMNAALDH1A1PRKCA
SCHEMBL29321926 0.92 LMNA (0.49) MAPTMAPK1LMNAALDH1A1PRKCA
SCHEMBL19161172 0.92 LMNA (0.49) MAPTMAPK1LMNAALDH1A1PRKCA
SCHEMBL29321833 0.92 LMNA (0.49) MAPTMAPK1LMNAALDH1A1PRKCA
SCHEMBL18641726 0.92 LMNA (0.49) MAPTMAPK1LMNAALDH1A1PRKCA
SCHEMBL22645881 0.92 LMNA (0.49) MAPTMAPK1LMNAALDH1A1PRKCA
SCHEMBL25629202 0.91 MAPT (0.49) MAPTMAPK1LMNAALDH1A1PRKCA
SCHEMBL30989590 0.91 LMNA (0.48) MAPTMAPK1LMNAALDH1A1PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3718565-B1 RESPIRATORY VIRUS VACCINES MODERNATX INC (US) 2022-04-27 EP disclosed