SCHEMBL18665374

SCHEMBL18665374

CCCCCCCCCOC(=O)CCCCCCCN(CCCCCCCC(=O)OC(CCCCCCCC)CCCCCCCC)C[C@@H](C)O

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.49
ALDH1A1 P00352 1/20 0.49
MAPT P10636 2/20 0.47
PRKCA P17252 1/20 0.46
PRKCE Q02156 1/20 0.46
PRKCQ Q04759 1/20 0.46
PRKCD Q05655 1/20 0.46
DNM1 Q05193 1/20 0.46
DGKA P23743 1/20 0.46
MAPK1 P28482 1/20 0.45
FABP3 P05413 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
NR5A2 O00482 1/20 0.42
NR5A1 Q13285 1/20 0.42
LPAR1 Q92633 2/20 0.42
LPAR3 Q9UBY5 2/20 0.42
ENPP2 Q13822 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22645879 1.00 LMNA (0.49) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL22645881 1.00 LMNA (0.49) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL29321833 1.00 LMNA (0.49) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL19161172 1.00 LMNA (0.49) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL29321926 1.00 LMNA (0.49) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL31065291 1.00 LMNA (0.49) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL18641726 1.00 LMNA (0.49) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL30989590 0.99 LMNA (0.48) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL25037492 0.92 ALDH1A1 (0.50) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL21845192 0.92 LMNA (0.50) LMNAALDH1A1MAPTPRKCAPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078082-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2026-03-19 US disclosed
US-20260069549-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2026-03-12 US disclosed
EP-4186888-B1 COMPOUND AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2025-11-26 EP disclosed
US-12404232-B2 Compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2025-09-02 US disclosed
US-20250228777-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2025-07-17 US disclosed
US-12324859-B2 Compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2025-06-10 US disclosed
US-12263248-B2 Compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2025-04-01 US disclosed
US-12151995-B2 Compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2024-11-26 US disclosed
US-20240238210-A1 POLYNUCLEOTIDES ENCODING CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR FOR THE TREATMENT OF CYSTIC FIBROSIS ARES CAPITAL CORPORATION, AS AGENT 2024-07-18 US disclosed
US-20240238210-A1 POLYNUCLEOTIDES ENCODING CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR FOR THE TREATMENT OF CYSTIC FIBROSIS ARES CAPITAL CORPORATION, AS AGENT 2024-07-18 US disclosed
US-20170210697-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2017-07-27 US disclosed
US-20170210697-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2017-07-27 US disclosed
WO-2017127750-A1 MESSENGER RIBONUCLEIC ACIDS FOR THE PRODUCTION OF INTRACELLULAR BINDING POLYPEPTIDES AND METHODS OF USE THEREOF MODERNATX, INC. (US) 2017-07-27 WO disclosed
WO-2017106799-A1 POLYNUCLEOTIDES ENCODING METHYLMALONYL-CoA MUTASE MODERNATX, INC. (US) 2017-06-22 WO disclosed
WO-2017099823-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS MODERNATX, INC. (US) 2017-06-15 WO disclosed
WO-2017070624-A1 TROPICAL DISEASE VACCINES MODERNATX, INC. (US) 2017-04-27 WO disclosed
WO-2017070613-A1 HUMAN CYTOMEGALOVIRUS VACCINE MODERNATX, INC. (US) 2017-04-27 WO disclosed
WO-2017070618-A1 CANCER VACCINES MODERNATX, INC. (US) 2017-04-27 WO disclosed
WO-2017070616-A2 SEXUALLY TRANSMITTED DISEASE VACCINES MODERNATX, INC. (US) 2017-04-27 WO disclosed
WO-2017049245-A2 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX, INC. (US) 2017-03-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170210697-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS LNPK, PLTP, PLIN3 LMNA 1539/4885ALDH1A1 4530/4885MAPT 2478/4885
US-12324859-B2 Compounds and compositions for intracellular delivery of therapeutic agents LNPK, PLTP, PLIN3 LMNA 1539/4885ALDH1A1 4530/4885MAPT 2478/4885
US-12151995-B2 Compounds and compositions for intracellular delivery of therapeutic agents LNPK, PLTP, PLIN3 LMNA 1539/4885ALDH1A1 4530/4885MAPT 2478/4885
US-12263248-B2 Compounds and compositions for intracellular delivery of therapeutic agents LNPK, PLTP, PLIN3 LMNA 1539/4885ALDH1A1 4530/4885MAPT 2478/4885
US-20260078082-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS PHOSPHO1, LIPC, SDCBP LMNA 455/4885ALDH1A1 4429/4885MAPT 2007/4885
US-20240238210-A1 POLYNUCLEOTIDES ENCODING CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR FOR THE TREATMENT OF CYSTIC FIBROSIS CFTR, SLC47A1, TMEM205 LMNA 2139/4885ALDH1A1 3662/4885MAPT 4836/4885
US-20260069549-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS SIN3A, PLIN3, MSR1 LMNA 1487/4885ALDH1A1 4755/4885MAPT 4504/4885
US-12404232-B2 Compounds and compositions for intracellular delivery of therapeutic agents LNPK, PLTP, PLIN3 LMNA 1539/4885ALDH1A1 4530/4885MAPT 2478/4885
US-20250228777-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS LNPK, PLTP, PLIN3 LMNA 1539/4885ALDH1A1 4530/4885MAPT 2478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.