SCHEMBL24372667

SCHEMBL24372667

c1ccc(-c2cccc3c(N(c4ccc5c(ccc6c7ccccc7ccc56)c4)c4ccc5oc6ccccc6c5c4)cccc23)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 7/20 0.38
▸ ALDH1A1 P00352 7/20 0.38
▸ MAPT P10636 5/20 0.38
▸ HPGD P15428 4/20 0.38
▸ TSHR P16473 2/20 0.38
▸ HSD17B10 Q99714 2/20 0.38
▸ ALOX15 P16050 1/20 0.38
▸ CASP1 P29466 1/20 0.38
▸ CASP7 P55210 1/20 0.38
▸ GLA P06280 2/20 0.37
▸ HTT P42858 1/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ KMT2A Q03164 3/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ GAA P10253 2/20 0.35
▸ SIRT2 Q8IXJ6 2/20 0.35
▸ SIRT1 Q96EB6 2/20 0.35
▸ GPR55 Q9Y2T6 1/20 0.34
▸ HNF4A P41235 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26045842 0.93 KDM4E (0.40) KDM4EALDH1A1MAPTHPGDTSHR
SCHEMBL26057755 0.91 KDM4E (0.38) KDM4EALDH1A1MAPTHPGDTSHR
SCHEMBL24372697 0.90 KDM4E (0.39) KDM4EALDH1A1MAPTHPGDTSHR
SCHEMBL24372695 0.90 KDM4E (0.40) KDM4EALDH1A1MAPTHPGDTSHR
SCHEMBL24372696 0.89 KDM4E (0.41) KDM4EALDH1A1MAPTHPGDTSHR
SCHEMBL17737637 0.89 KDM4E (0.41) KDM4EALDH1A1MAPTHPGDTSHR
SCHEMBL25578879 0.89 KDM4E (0.37) KDM4EALDH1A1MAPTHPGDTSHR
SCHEMBL25088632 0.89 KDM4E (0.35) KDM4EALDH1A1MAPTHPGDTSHR
SCHEMBL25088654 0.89 KDM4E (0.37) KDM4EALDH1A1MAPTHPGDTSHR
SCHEMBL23238901 0.89 KDM4E (0.36) KDM4EALDH1A1MAPTHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230165142-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-05-25 — — US disclosed
US-20230165142-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-05-25 — — US disclosed
US-20230141672-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-05-11 — — US disclosed
US-20230141672-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-05-11 — — US disclosed
US-20230139032-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-05-04 — — US disclosed
US-20230139032-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-05-04 — — US disclosed
US-20220131083-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-04-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230141672-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME NECTIN4, SOD1, ELAVL1 KDM4E 2176/4885ALDH1A1 1700/4885MAPT 2415/4885
US-20230165142-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE ELAVL1, LIMS1, ZNF436-AS1 KDM4E 1563/4885ALDH1A1 1311/4885MAPT 1472/4885
US-20230139032-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME NECTIN4, L1CAM, EPHA6 KDM4E 2955/4885ALDH1A1 1764/4885MAPT 1927/4885
US-20220131083-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TELO2, TERT, LIMS1 KDM4E 3373/4885ALDH1A1 275/4885MAPT 2033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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