Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1454134 | 0.87 | TDP1 (0.44) | GAAHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL24380499 | 0.78 | MAPT (0.45) | HPGDKMT2AMEN1ALDH1A1SRD5A2 | |
| SCHEMBL28534675 | 0.78 | MAPT (0.45) | HPGDKMT2AMEN1ALDH1A1SRD5A2 | |
| SCHEMBL1149394 | 0.76 | IDO1 (0.58) | KMT2AALDH1A1SRD5A2IDO1HTT | |
| SCHEMBL11410252 | 0.76 | IDO1 (0.58) | KMT2AALDH1A1SRD5A2IDO1HTT | |
| SCHEMBL10870481 | 0.76 | KMT2A (0.66) | HPGDKMT2AMEN1ALDH1A1SRD5A2 | |
| SCHEMBL13154485 | 0.76 | TP53 (0.40) | KMT2AMEN1ALDH1A1IDO1LMNA | |
| SCHEMBL1106683 | 0.76 | MEN1 (0.60) | KMT2AMEN1ALDH1A1SRD5A2MAPT | |
| SCHEMBL24047166 | 0.75 | LOXL2 (0.45) | GAAKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL24025403 | 0.74 | SLC6A4 (0.45) | LMNASLC6A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087216-A1 | DOUBLE DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-04-28 | — | — | WO | disclosed |