Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2444509 | 0.72 | P2RX4 (0.35) | ALDH1A1SMN1; SMN2HPGDKMT2AMAPT | |
| SCHEMBL25091841 | 0.69 | KDM4E (0.37) | KDM4EKMT2AMEN1 | |
| SCHEMBL7514655 | 0.68 | CA12 (0.39) | KDM4EALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL2381115 | 0.64 | THRB (0.32) | KDM4EALDH1A1SMN1; SMN2HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL10489477 | 0.61 | KMT2A (0.35) | KDM4EALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL6226194 | 0.58 | P2RX4 (0.47) | KDM4EALDH1A1SMN1; SMN2TDP1KMT2A | |
| SCHEMBL4625362 | 0.58 | — | — | |
| SCHEMBL25060078 | 0.57 | DAO (0.36) | ALDH1A1SMN1; SMN2TDP1HPGDKMT2A | |
| SCHEMBL25038288 | 0.57 | KDM4E (0.33) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL13299219 | 0.56 | DRD2 (0.32) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011104337-A1 | HETEROCYCLOALKYL-CONTAINING THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-09-01 | — | — | WO | disclosed |