Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.50 |
| ▸ | ADH1B | P00325 | 3/20 | 0.47 |
| ▸ | ADH1A | P07327 | 3/20 | 0.47 |
| ▸ | ADH7 | P40394 | 3/20 | 0.47 |
| ▸ | ADH1C | P00326 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | ADH4 | P08319 | 1/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2183070 | 0.94 | ADH1B (0.45) | PAOXADH1BADH1AADH7ADH1C | |
| SCHEMBL1785087 | 0.86 | GNAI3 (0.44) | PAOXADH1BADH1AADH7ADH1C | |
| SCHEMBL20407305 | 0.86 | — | — | |
| SCHEMBL16207271 | 0.86 | ADH1B (0.46) | PAOXADH1BADH1AADH7ADH1C | |
| SCHEMBL1781619 | 0.82 | HRH3 (0.52) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL4392290 | 0.81 | PAOX (0.48) | PAOXGNAI3GNAO1GNAI1SIGMAR1 | |
| SCHEMBL3931949 | 0.81 | ADH1B (0.48) | PAOXADH1BADH1AADH7ADH1C | |
| SCHEMBL3950791 | 0.81 | ADH1B (0.54) | PAOXADH1BADH1AADH7ADH1C | |
| SCHEMBL23259267 | 0.81 | PAOX (0.42) | PAOXGNAI3GNAO1GNAI1SIGMAR1 | |
| SCHEMBL13527580 | 0.80 | HRH3 (0.56) | ADH1BADH1AADH7ADH1CEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087216-A1 | DOUBLE DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-04-28 | — | — | WO | disclosed |