Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14485973 | 0.84 | AXL (0.39) | CYP1A2ALDH1A1AXL | |
| SCHEMBL8404446 | 0.84 | CYP1A2 (0.47) | CYP1A2ALDH1A1CYP2A6CCR1CCR5 | |
| SCHEMBL12245721 | 0.76 | AXL (0.60) | CYP1A2ALDH1A1AXL | |
| SCHEMBL24724775 | 0.76 | AXL (0.55) | CYP1A2ALDH1A1AXLCYP2A6 | |
| SCHEMBL18630339 | 0.71 | CYP1A2 (0.36) | CYP1A2CYP2A6CCR1CCR5CCR8 | |
| SCHEMBL20502331 | 0.71 | CYP1A2 (0.36) | CYP1A2AXLCYP2A6 | |
| SCHEMBL2494204 | 0.71 | CYP1A2 (0.36) | CYP1A2ALDH1A1AXLCYP2A6CCR1 | |
| SCHEMBL23579000 | 0.71 | CSNK2A1 (0.38) | ALDH1A1 | |
| SCHEMBL2551647 | 0.71 | NOS3 (0.45) | AXL | |
| SCHEMBL15460042 | 0.71 | NOS3 (0.45) | AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3596051-B1 | FUSED BICYCLIC COMPOUNDS, COMPOSITIONS AND APPLICATIONS THEREOF | IMPETIS BIOSCIENCES LTD (IN) | 2022-04-27 | — | — | EP | disclosed |