Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2442455 | 0.88 | LMNA (0.37) | LMNAMEN1CYP3A4ALOX15MAPK1 | |
| SCHEMBL2443263 | 0.85 | LMNA (0.40) | LMNAMEN1CYP3A4ALOX15MAPK1 | |
| SCHEMBL2441048 | 0.83 | LMNA (0.38) | LMNAMEN1CYP3A4ALOX15MAPK1 | |
| SCHEMBL2438290 | 0.82 | LMNA (0.36) | LMNAMEN1CYP3A4ALOX15MAPK1 | |
| SCHEMBL2443037 | 0.80 | LMNA (0.42) | LMNAMEN1CYP3A4ALOX15MAPK1 | |
| SCHEMBL11883068 | 0.80 | TRPA1 (0.42) | NR1H3 | |
| SCHEMBL15012441 | 0.78 | LMNA (0.42) | LMNAMEN1CYP3A4ALOX15MAPK1 | |
| SCHEMBL10532824 | 0.78 | LMNA (0.42) | LMNAMEN1CYP3A4ALOX15MAPK1 | |
| SCHEMBL15012463 | 0.78 | LMNA (0.42) | LMNAMEN1CYP3A4ALOX15MAPK1 | |
| SCHEMBL15012464 | 0.78 | LMNA (0.42) | LMNAMEN1CYP3A4ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362765-A2 | PERFUME SYSTEMS | The Procter & Gamble Company (US) | 2011-09-07 | — | — | EP | claimed |
| WO-2010065446-A2 | PERFUME SYSTEMS | THE PROCTER & GAMBLE COMPANY (US) | 2010-06-10 | — | — | WO | claimed |