Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21840508 | 0.81 | ALDH1A1 (0.43) | HSD17B10MAPTKMT2AALDH1A1GAA | |
| SCHEMBL12332375 | 0.79 | GRN (0.38) | KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL162657 | 0.76 | NPSR1 (0.41) | F2HSD17B10MAPTKMT2ANPSR1 | |
| SCHEMBL6100678 | 0.76 | MAPK1 (0.43) | F2HSD17B10MAPTKMT2ANPSR1 | |
| SCHEMBL28168679 | 0.76 | KDM4E (0.44) | F2HSD17B10MAPTKMT2ANPSR1 | |
| SCHEMBL10067534 | 0.75 | ALDH1A1 (0.38) | F2HSD17B10MAPTKMT2ANPSR1 | |
| SCHEMBL31478620 | 0.74 | F2 (0.40) | F2HSD17B10MAPTKMT2ANPSR1 | |
| SCHEMBL3706189 | 0.73 | KDM4E (0.42) | F2HSD17B10MAPTKMT2ANPSR1 | |
| SCHEMBL6975840 | 0.71 | NPSR1 (0.38) | F2HSD17B10MAPTKMT2ANPSR1 | |
| SCHEMBL29951090 | 0.71 | ALDH1A1 (0.38) | F2HSD17B10MAPTKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3642199-B1 | BENZOFURANS AS IRAK4 MODULATORS | HOFFMANN LA ROCHE (CH) | 2022-04-27 | — | — | EP | disclosed |