Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23107315 | 0.81 | IRAK4 (0.34) | IRAK4MGLLMAP4K1 | |
| SCHEMBL24375510 | 0.81 | IRAK4 (0.34) | IRAK4MGLLMAP4K1 | |
| SCHEMBL23541778 | 0.81 | IRAK4 (0.34) | IRAK4MGLLMAP4K1 | |
| SCHEMBL21888895 | 0.80 | MGLL (0.33) | IRAK4MGLLMAP4K1 | |
| SCHEMBL23674342 | 0.79 | MGLL (0.32) | IRAK4MGLLMAP4K1 | |
| SCHEMBL23104618 | 0.79 | MGLL (0.32) | IRAK4MGLLMAP4K1 | |
| SCHEMBL23104199 | 0.79 | MGLL (0.32) | IRAK4MGLLMAP4K1 | |
| SCHEMBL23541704 | 0.79 | NLRP3 (0.43) | — | |
| SCHEMBL24871972 | 0.77 | IRAK4 (0.35) | IRAK4MGLLMAP4K1 | |
| SCHEMBL23103362 | 0.77 | MGLL (0.32) | IRAK4MGLLMAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3642199-B1 | BENZOFURANS AS IRAK4 MODULATORS | HOFFMANN LA ROCHE (CH) | 2022-04-27 | — | — | EP | disclosed |