SCHEMBL24375902

SCHEMBL24375902

CCc1ccc(N(C)C2CNC2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 8/20 0.38
SLC6A4 P31645 8/20 0.38
SLC6A3 Q01959 8/20 0.38
NISCH Q9Y2I1 1/20 0.35
CYP3A4 P08684 4/20 0.35
CYP2D6 P10635 3/20 0.35
CYP2C9 P11712 3/20 0.35
CYP2C19 P33261 3/20 0.35
CYP1A2 P05177 2/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
KCNH2 Q12809 1/20 0.34
ALDH1A1 P00352 2/20 0.33
CHIT1 Q13231 1/20 0.33
CHIA Q9BZP6 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19639893 0.82 HTR2A (0.41) NISCHCYP3A4HTR2AHTR2CALDH1A1
SCHEMBL19639881 0.81 HRH3 (0.42) CYP3A4HTR2AHTR2CALDH1A1TSHR
SCHEMBL19639917 0.79 HRH3 (0.44) CYP3A4HTR2AHTR2CALDH1A1TSHR
SCHEMBL23255375 0.79 ALDH1A1 (0.44) SLC6A2SLC6A4SLC6A3NISCHHTR2C
SCHEMBL23830552 0.76 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6
SCHEMBL17484556 0.75 RORC (0.39) HTR2AHTR2C
SCHEMBL28531862 0.74 KCNH2 (0.42) CYP3A4CYP2D6CYP2C9CYP2C19HTR2A
SCHEMBL10265352 0.68 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2HPGDTAAR1TP53
SCHEMBL44501 0.68 ALDH1A1 (0.67) CYP3A4ALDH1A1SMN1; SMN2TSHRMAPK1
SCHEMBL17485895 0.68 CHKA (0.47) CYP3A4ALDH1A1SMN1; SMN2TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022086085-A1 BENZIMIDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, AND USE THEREOF 고려대학교 산학협력단 2022-04-28 WO disclosed