Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.50 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5033226 | 0.91 | GAA (0.56) | RARBTSHRLMNAMEN1ALDH1A1 | |
| SCHEMBL5033563 | 0.88 | TP53 (0.62) | RARBTSHRLMNAGAARAB9A | |
| SCHEMBL3001656 | 0.86 | TP53 (0.65) | RARBTSHRLMNAGAARAB9A | |
| SCHEMBL3001402 | 0.86 | TP53 (0.65) | RARBTSHRLMNAGAARAB9A | |
| SCHEMBL5502709 | 0.86 | TP53 (0.65) | RARBTSHRLMNAGAARAB9A | |
| SCHEMBL9781935 | 0.84 | L3MBTL1 (0.56) | TSHRLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10629620 | 0.84 | RARB (0.64) | RARBTSHRLMNAMEN1USP2 | |
| SCHEMBL17253328 | 0.83 | RARB (0.65) | RARBTSHRLMNACYP3A4GAA | |
| SCHEMBL12243089 | 0.83 | RARB (0.65) | RARBTSHRLMNACYP3A4GAA | |
| SCHEMBL12243087 | 0.82 | RARB (0.68) | RARBTSHRLMNACYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3988098-A1 | HETEROCYCLO ALKYL COMPOUNDS USED AS CCR2/CCR5 ANTAGONIST | Shenzhen Lingfang Biotech Co., Ltd (CN) | 2022-04-27 | — | — | EP | disclosed |