SCHEMBL24377032

SCHEMBL24377032

c1ccc(-c2ccc(-c3ccccc3)c(-c3ccc4cc(-c5nc(-c6ccc7ccccc7c6)nc(-c6ccc7ccccc7c6)n5)ccc4c3)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.46
ESR2 Q92731 3/20 0.46
GSTP1 P09211 1/20 0.46
KDM4E B2RXH2 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
ALDH1A1 P00352 1/20 0.45
TP53 P04637 1/20 0.45
CYP1A2 P05177 1/20 0.45
HSD17B10 Q99714 1/20 0.45
CYP17A1 P05093 1/20 0.45
CYP19A1 P11511 1/20 0.45
CYP11B1 P15538 1/20 0.45
CYP11B2 P19099 1/20 0.45
ADORA2A P29274 2/20 0.44
ADORA1 P30542 2/20 0.44
HSD17B1 P14061 2/20 0.43
HSD17B2 P37059 2/20 0.43
CYP1A1 P04798 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24377047 1.00 ESR1 (0.46) ESR1ESR2GSTP1KDM4EMEN1
SCHEMBL26592311 0.97 HSD17B1 (0.45) ESR1ESR2GSTP1KDM4EMEN1
SCHEMBL26592326 0.97 HSD17B1 (0.45) ESR1ESR2GSTP1KDM4EMEN1
SCHEMBL26592252 0.97 HSD17B1 (0.45) ESR1ESR2GSTP1KDM4EMEN1
SCHEMBL26592235 0.97 HSD17B1 (0.45) ESR1ESR2GSTP1KDM4EMEN1
SCHEMBL24377048 0.97 MEN1 (0.47) ESR1ESR2GSTP1KDM4EMEN1
SCHEMBL26592321 0.95 MEN1 (0.45) ESR1ESR2GSTP1KDM4EMEN1
SCHEMBL26592310 0.95 MEN1 (0.45) ESR1ESR2GSTP1KDM4EMEN1
SCHEMBL21481340 0.95 HSD17B1 (0.44) ESR1ESR2GSTP1KDM4EMEN1
SCHEMBL26592245 0.95 MEN1 (0.45) ESR1ESR2GSTP1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220131082-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2022-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220131082-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF NFE2L2, OR51E2, ETV6 ESR1 5/4885ESR2 79/4885GSTP1 2312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.