Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | HTR5A | P47898 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220704 | 0.78 | AKR1B1 (0.42) | HTR2CDRD2HTR2AHIF1AAKR1B1 | |
| SCHEMBL12301085 | 0.78 | KDM4E (0.36) | HTR2CHTR5AADRA2ACYP1A2MAPT | |
| SCHEMBL19030108 | 0.78 | AKR1B1 (0.34) | HTR2CDRD2HTR2ACA1CA2 | |
| SCHEMBL17193793 | 0.76 | AKR1B1 (0.35) | HTR2CDRD2HTR2ACA1CA2 | |
| SCHEMBL19030580 | 0.74 | HTR2C (0.39) | HTR2CDRD2HTR2ACA1CA2 | |
| SCHEMBL30677841 | 0.73 | HTR2C (0.35) | HTR2CDRD2HTR2ACA1CA2 | |
| SCHEMBL19030507 | 0.73 | HTR2C (0.41) | HTR2CDRD2HTR2ACNR1KDM1A | |
| SCHEMBL19030789 | 0.73 | HIF1A (0.36) | HTR2CDRD2HTR2AKDM1AHIF1A | |
| SCHEMBL18474240 | 0.73 | AKR1B1 (0.36) | HTR2CDRD2HTR2ACA1CA2 | |
| SCHEMBL3122824 | 0.72 | MAOA (0.39) | DRD2HTR2AADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022082337-A1 | PROCESS OF PREPARING 3-FLUORO-5 ( ( (1R, 2AR) -3, 3, 4, 4-TETRAFLUORO-1, 2A-DIHYDROXY-2, 2A, 3, 4-TETRAHYDRO-1H-CYCLOPENTA [CD] INDEN-7-YL) OXY) BENZONITRILE | NIKANG THERAPEUTICS, INC. (US) | 2022-04-28 | — | — | WO | disclosed |