Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24377052 | 0.85 | PDE7A (0.35) | PDE7APREPCES1L3MBTL1CA12 | |
| SCHEMBL31003737 | 0.82 | PDE7A (0.39) | PDE7ACES1ACHE | |
| SCHEMBL31355605 | 0.80 | PREP (0.34) | PREPCA12CA1CA9 | |
| SCHEMBL31003677 | 0.78 | ADAM17 (0.38) | PDE7APREPL3MBTL1 | |
| SCHEMBL31184980 | 0.76 | PDE7A (0.31) | PDE7APREPL3MBTL1 | |
| SCHEMBL23973910 | 0.68 | PDE7A (0.39) | PDE7ACES1ACHE | |
| SCHEMBL24377411 | 0.68 | PDE7A (0.39) | PDE7ACES1ACHE | |
| SCHEMBL22111804 | 0.67 | CNR1 (0.43) | PDE7ACES1ACHE | |
| SCHEMBL5656464 | 0.67 | MAPT (0.59) | PREPCA12CA1CA9 | |
| SCHEMBL22111802 | 0.65 | PDE7A (0.39) | PDE7ACES1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118812517-A | Antitumor compounds as UPR agonists and uses thereof | 南京圣和药业股份有限公司 | 2024-10-22 | — | — | CN | disclosed |
| WO-2022087234-A1 | ANTICANCER COMPOUNDS SELECTIVE FOR ER-POSITIVE CANCERS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2022-04-28 | — | — | WO | disclosed |