Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24377053 | 0.85 | PDE7A (0.35) | PDE7AL3MBTL1PREPCES1CA12 | |
| SCHEMBL22111802 | 0.82 | PDE7A (0.39) | PDE7ACES1POLBCASP6ACHE | |
| SCHEMBL31003697 | 0.80 | POLB (0.36) | PREPBRD4POLBCASP6CA12 | |
| SCHEMBL22076823 | 0.79 | GPR55 (0.45) | PDE7ACES1POLBCASP6ACHE | |
| SCHEMBL31003677 | 0.78 | ADAM17 (0.38) | PDE7AL3MBTL1PREPBRD4 | |
| SCHEMBL31184980 | 0.76 | PDE7A (0.31) | PDE7AL3MBTL1PREP | |
| SCHEMBL3076828 | 0.76 | MMP2 (0.46) | — | |
| SCHEMBL31355583 | 0.71 | DYRK3 (0.41) | PDE7ABRD4POLBCASP6 | |
| SCHEMBL22076813 | 0.70 | CNR1 (0.47) | L3MBTL1BRD4POLBCASP6CNR1 | |
| SCHEMBL11733669 | 0.69 | PDE7A (0.47) | PDE7ACES1POLBACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118812517-A | Antitumor compounds as UPR agonists and uses thereof | 南京圣和药业股份有限公司 | 2024-10-22 | — | — | CN | disclosed |
| WO-2024175114-A1 | BORON CONTAINING COMPOUNDS AND THERAPEUTIC USES THEREOF | Shanghai Yuyao Biotech Ltd. (CN) | 2024-08-29 | — | — | WO | disclosed |
| US-20230391721-A1 | ANTICANCER COMPOUNDS SELECTIVE FOR ER-POSITIVE CANCERS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-12-07 | — | — | US | disclosed |
| CN-116723841-A | Anticancer compounds selective for ER-positive cancers | 伊利诺伊大学董事会 | 2023-09-08 | — | — | CN | disclosed |
| EP-4232038-A1 | ANTICANCER COMPOUNDS SELECTIVE FOR ER-POSITIVE CANCERS | The Board of Trustees of the University of Illinois (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022087234-A1 | ANTICANCER COMPOUNDS SELECTIVE FOR ER-POSITIVE CANCERS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2022-04-28 | — | — | WO | disclosed |
| WO-2022087234-A1 | ANTICANCER COMPOUNDS SELECTIVE FOR ER-POSITIVE CANCERS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2022-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230391721-A1 | ANTICANCER COMPOUNDS SELECTIVE FOR ER-POSITIVE CANCERS | ESR1, ESR2, ESRRG | PDE7A 3103/4885L3MBTL1 825/4885PREP 1548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.