Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HINT1 | P49773 | 1/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25389665 | 1.00 | KDM4E (0.49) | KDM4ETAS1R3TAS1R1P2RX3P2RX4 | |
| SCHEMBL29973219 | 0.97 | KDM4E (0.49) | KDM4ETAS1R3TAS1R1P2RX3P2RX4 | |
| SCHEMBL24377105 | 0.97 | KDM4E (0.49) | KDM4ETAS1R3TAS1R1P2RX3P2RX4 | |
| SCHEMBL25387607 | 0.97 | KDM4E (0.49) | KDM4ETAS1R3TAS1R1P2RX3P2RX4 | |
| SCHEMBL26347587 | 0.91 | KDM4E (0.56) | KDM4ETAS1R3TAS1R1ALDH1A1HPGD | |
| SCHEMBL24181915 | 0.91 | KDM4E (0.56) | KDM4ETAS1R3TAS1R1ALDH1A1HPGD | |
| SCHEMBL29479237 | 0.89 | KDM4E (0.53) | KDM4ETAS1R3TAS1R1TAAR1HPGD | |
| SCHEMBL13637338 | 0.88 | KDM4E (0.54) | KDM4ETAS1R3TAS1R1ALDH1A1HPGD | |
| SCHEMBL21566437 | 0.88 | KDM4E (0.54) | KDM4ETAS1R3TAS1R1ALDH1A1HPGD | |
| SCHEMBL4499258 | 0.88 | KDM4E (0.54) | KDM4ETAS1R3TAS1R1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4242218-A1 | MULTIFUNCTIONAL CYCLIC DINUCLEOTIDE AND USE THEREOF | Tyligand Bioscience (Shanghai) Limited (CN) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022083584-A1 | MULTIFUNCTIONAL CYCLIC DINUCLEOTIDE AND USE THEREOF | 泰励生物科技（上海）有限公司 | 2022-04-28 | — | — | WO | disclosed |