SCHEMBL29479237

SCHEMBL29479237

CC(C)C(=O)Nc1nc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](OC(=O)c3ccccc3)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.53
▸ TAS1R3 Q7RTX0 2/20 0.53
▸ TAS1R1 Q7RTX1 2/20 0.53
▸ HPGD P15428 1/20 0.47
▸ TAAR1 Q96RJ0 2/20 0.47
▸ HINT1 P49773 1/20 0.44
▸ ENPP1 P22413 1/20 0.44
▸ IMPDH2 P12268 1/20 0.43
▸ P2RY11 Q96G91 1/20 0.43
▸ PNP P00491 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31401856 0.92 KDM4E (0.52) KDM4ETAS1R3TAS1R1HPGDTAAR1
SCHEMBL18520965 0.89 TAS1R3 (0.59) KDM4ETAS1R3TAS1R1HPGDHINT1
SCHEMBL25387607 0.89 KDM4E (0.49) KDM4ETAS1R3TAS1R1HPGDTAAR1
SCHEMBL24377105 0.89 KDM4E (0.49) KDM4ETAS1R3TAS1R1HPGDTAAR1
SCHEMBL24377219 0.89 KDM4E (0.49) KDM4ETAS1R3TAS1R1HPGDTAAR1
SCHEMBL25389665 0.89 KDM4E (0.49) KDM4ETAS1R3TAS1R1HPGDTAAR1
SCHEMBL29973219 0.89 KDM4E (0.49) KDM4ETAS1R3TAS1R1HPGDTAAR1
SCHEMBL20210330 0.87 KDM4E (0.58) KDM4ETAS1R3TAS1R1HPGDHINT1
SCHEMBL21878146 0.87 KDM4E (0.58) KDM4ETAS1R3TAS1R1HPGDHINT1
SCHEMBL22883375 0.87 KDM4E (0.58) KDM4ETAS1R3TAS1R1HPGDHINT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4653017-A1 ANTIBODY-DRUG CONJUGATE AND USE THEREOF Tyligand Bioscience (Shanghai) Limited (CN) 2025-11-26 — — EP disclosed
CN-118873678-A Antibody-conjugated drugs and uses thereof 泰励生物科技(上海)有限公司 2024-11-01 — — CN disclosed
WO-2024153127-A1 ANTIBODY-DRUG CONJUGATE AND USE THEREOF 泰励生物科技(上海)有限公司 2024-07-25 — — WO disclosed
US-20240059729-A1 MULTIFUNCTIONAL CYCLIC DINUCLEOTIDE AND USE THEREOF TYLIGAND BIOSCIENCE (SHANGHAI) LIMITED (CN) 2024-02-22 — — US disclosed
CN-117015383-A Multifunctional cyclic dinucleotide and application thereof 泰励生物科技(上海)有限公司 2023-11-07 — — CN disclosed
EP-4242218-A1 MULTIFUNCTIONAL CYCLIC DINUCLEOTIDE AND USE THEREOF Tyligand Bioscience (Shanghai) Limited (CN) 2023-09-13 — — EP disclosed
CN-115160392-A Multifunctional cyclic dinucleotide and application thereof 泰励生物科技(上海)有限公司 2022-10-11 — — CN disclosed
WO-2022083584-A1 MULTIFUNCTIONAL CYCLIC DINUCLEOTIDE AND USE THEREOF 泰励生物科技(上海)有限公司 2022-04-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240059729-A1 MULTIFUNCTIONAL CYCLIC DINUCLEOTIDE AND USE THEREOF MAVS, IRF3, STING1 KDM4E 2917/4885TAS1R3 4161/4885TAS1R1 4092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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