Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | GRK5 | P34947 | 1/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL28208001 | 0.98 | TSHR (0.56) | TSHRHTTALDH1A1CYP19A1MAPT | |
| SCHEMBL31481313 | 0.85 | MAPT (0.51) | TSHRHTTALDH1A1CYP19A1MAPT | |
| SCHEMBL899149 | 0.85 | TSHR (0.48) | TSHRHTTALDH1A1CYP19A1MAPT | |
| SCHEMBL29664408 | 0.85 | TSHR (0.48) | TSHRHTTALDH1A1CYP19A1MAPT | |
| SCHEMBL5864975 | 0.85 | TSHR (0.48) | TSHRHTTALDH1A1CYP19A1MAPT | |
| SCHEMBL5652028 | 0.85 | TSHR (0.48) | TSHRHTTALDH1A1CYP19A1MAPT | |
| SCHEMBL11843690 | 0.82 | TSHR (0.45) | TSHRHTTALDH1A1CYP19A1MAPT | |
| SCHEMBL10962494 | 0.82 | TSHR (0.45) | TSHRHTTALDH1A1CYP19A1MAPT | |
| SCHEMBL11847353 | 0.80 | TSHR (0.44) | TSHRHTTALDH1A1CYP19A1MAPT | |
| SCHEMBL18299386 | 0.80 | CYP1A2 (0.46) | TSHRHTTALDH1A1CYP19A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748852-A | A kind of synthetic method of 2,6- dimethyl -4- bromopyridine | 丹阳市宁大卫防检测技术有限公司 | 2019-05-14 | — | — | CN | claimed |
| CN-107162964-A | A kind of synthetic method of the bromopyridine of 2,6 dimethyl 4 | 刘瑞海 | 2017-09-15 | — | — | CN | claimed |
| US-9132115-B2 | Lipid raft, caveolin protein, and caveolar function modulation compounds and associated synthetic and therapeutic methods | KAY HEIDI (US) | 2015-09-15 | — | — | US | claimed |
| CN-104592200-A | Chiral paramagnetic probe using 1,4,7,10-tetraazacyclododecane as skeleton | UNIV NANKAI | 2015-05-06 | — | — | CN | claimed |
| US-20130253050-A1 | LIPID RAFT, CAVEOLIN PROTEIN,, AND CAVEOLAR FUNCTION MODULATION COMPOUNDS AND ASSOCIATED SYNTHETIC AND THERAPEUTIC METHODS | KAY HEIDI (US) | 2013-09-26 | — | — | US | claimed |
| US-8425921-B1 | Lipid raft, caveolin protein, and caveolar function modulation compounds and associated synthetic and therapeutic methods | KAY HEIDI (US) | 2013-04-23 | — | — | US | claimed |
| US-8026382-B2 | Lipid raft, caveolin protein, and caveolar function modulation compounds and associated synthetic and therapeutic methods | KAY HEIDI | 2011-09-27 | — | — | US | claimed |
| WO-2008144616-A1 | LIPID RAFT, CAVEOLIN PROTEIN, AND CAVEOLAR FUNCTION MODULATION COMPOUNDS AND ASSOCIATED SYNTHETIC AND THERAPEUTIC METHODS | KAY HEIDI (US) | 2008-11-27 | — | — | WO | claimed |
| US-20080286316-A1 | Lipid raft, caveolin protein, and caveolar function modulation compounds and associated synthetic and therapeutic methods | KAY HEIDI | 2008-11-20 | — | — | US | claimed |
| WO-2007006019-A1 | MATERIALS AND METHODS FOR SCREENING, DIAGNOSIS AND PROGNOSIS OF CONDITIONS ASSOCIATED WITH STAT PROTEIN EXPRESSION | UNIVERSITY OF SOUTH FLORIDA (US) | 2007-01-11 | — | — | WO | claimed |
| EP-0397474-B1 | Photosensitive composition | TOSHIBA KK (JP) | 1997-12-10 | — | — | EP | claimed |
| CN-117043153-A | Heterocyclic compounds as GLS1 inhibitors | 杭州紫晶医药科技有限公司 | 2023-11-10 | — | — | CN | disclosed |
| WO-2022122044-A1 | HETEROCYCLIC COMPOUND SERVING AS GLS1 INHIBITOR | 杭州紫晶医药科技有限公司 | 2022-06-16 | — | — | WO | disclosed |
| CN-109748852-A | A kind of synthetic method of 2,6- dimethyl -4- bromopyridine | 丹阳市宁大卫防检测技术有限公司 | 2019-05-14 | — | — | CN | disclosed |
| CN-109748852-A | A kind of synthetic method of 2,6- dimethyl -4- bromopyridine | 丹阳市宁大卫防检测技术有限公司 | 2019-05-14 | — | — | CN | disclosed |
| US-20100168077-A1 | Novel Pyridine Derivatives, Processes for Preparing Them, Pharmaceutical Compositions Thereof | UCB PHARMA, S.A. (BE) | 2010-07-01 | — | — | US | disclosed |
| WO-2009104167-A1 | A SUBSTANCE OR COMPOSITION FOR THE TREATMENT OF CANCER | MINTEK (ZA) | 2009-08-27 | — | — | WO | disclosed |
| WO-2007006019-A1 | MATERIALS AND METHODS FOR SCREENING, DIAGNOSIS AND PROGNOSIS OF CONDITIONS ASSOCIATED WITH STAT PROTEIN EXPRESSION | UNIVERSITY OF SOUTH FLORIDA (US) | 2007-01-11 | — | — | WO | disclosed |
| US-4038398-A | PROPHYLACTIC TREATMENT FOR ALLERGY AND ANAPHYLACTIC REACTIONS ION | THE UPJOHN COMPANY (US) | 1977-07-26 | — | — | US | disclosed |
| US-3963660-A | ANTI-ALLERGY | THE UPJOHN COMPANY (US) | 1976-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080286316-A1 | Lipid raft, caveolin protein, and caveolar function modulation compounds and associated synthetic and therapeutic methods | CD4, VAPB, PXMP4 | TSHR 1014/4885HTT 3069/4885ALDH1A1 4369/4885 |
| US-20130253050-A1 | LIPID RAFT, CAVEOLIN PROTEIN,, AND CAVEOLAR FUNCTION MODULATION COMPOUNDS AND ASSOCIATED SYNTHETIC AND THERAPEUTIC METHODS | VAPB, CD4, VAPA | TSHR 926/4885HTT 2834/4885ALDH1A1 4236/4885 |
| US-20100168077-A1 | Novel Pyridine Derivatives, Processes for Preparing Them, Pharmaceutical Compositions Thereof | CYP4B1, CYP3A4, CYP2C19 | TSHR 3902/4885HTT 3520/4885ALDH1A1 488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.