SCHEMBL24377639 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	CDK9	P50750	2/20	0.44

▸	CCNT1	O60563	1/20	0.44

▸	KMT2A	Q03164	1/20	0.39

▸	HTR1D	P28221	10/20	0.38

▸	SLC6A4	P31645	2/20	0.37

▸	HTR1E	P28566	2/20	0.36

▸	HTR1A	P08908	1/20	0.36

▸	RORC	P51449	1/20	0.35

▸	GABRA1	P14867	1/20	0.35

▸	GABRG2	P18507	1/20	0.35

▸	GABRB3	P28472	1/20	0.35

▸	GABRA3	P34903	1/20	0.35

▸	GABRA2	P47869	1/20	0.35

▸	GABRB2	P47870	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24377638	0.85	SLC6A4 (0.38)	CDK9CCNT1HTR1DSLC6A4HTR1E
SCHEMBL24377636	0.78	SLC6A4 (0.45)	HTR1DSLC6A4HTR1EHTR1A
SCHEMBL24377907	0.75	HTR1D (0.41)	CDK9HTR1DSLC6A4HTR1EHTR1A
SCHEMBL17207872	0.74	CDK9 (0.42)	CDK9CCNT1KMT2ARORC
SCHEMBL31482898	0.70	CDK9 (0.45)	CDK9CCNT1KMT2ARORC
SCHEMBL15747391	0.70	CDK9 (0.45)	CDK9CCNT1KMT2ARORC
SCHEMBL20719178	0.70	CDK9 (0.41)	CDK9CCNT1KMT2ARORC
SCHEMBL2547781	0.70	CDK9 (0.48)	CDK9CCNT1KMT2ARORC
SCHEMBL2547779	0.70	CDK9 (0.48)	CDK9CCNT1KMT2ARORC
SCHEMBL2541999	0.70	RORC (0.45)	CDK9CCNT1KMT2ARORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022083560-A1	TYK2 SELECTIVE INHIBITOR AND USE THEREOF	南京药石科技股份有限公司	2022-04-28	—	—	WO	disclosed