Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.65 |
| ▸ | PPARG | P37231 | 10/20 | 0.65 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2440054 | 0.86 | PPARA (0.61) | PPARAPPARGCYP4F2CYP4A11TDP1 | |
| SCHEMBL3939774 | 0.84 | PPARA (0.51) | PPARAPPARGCYP4F2CYP4A11 | |
| SCHEMBL9167497 | 0.81 | FFAR1 (0.56) | PPARAPPARGCYP4F2CYP4A11TDP1 | |
| SCHEMBL10444982 | 0.81 | PPARA (0.61) | PPARAPPARGCYP4F2CYP4A11TDP1 | |
| SCHEMBL1802183 | 0.81 | ALDH1A1 (0.56) | PPARAPPARGCYP4F2CYP4A11TDP1 | |
| SCHEMBL3840661 | 0.81 | PPARG (0.71) | PPARAPPARGCYP4F2CYP4A11PPARD | |
| SCHEMBL17274722 | 0.81 | PPARA (0.80) | PPARAPPARGCYP4F2CYP4A11FBP1 | |
| SCHEMBL4425984 | 0.80 | CYP4F2 (0.64) | PPARAPPARGCYP4F2CYP4A11TDP1 | |
| SCHEMBL3848011 | 0.80 | PPARA (0.69) | PPARAPPARGCYP4F2CYP4A11PPARD | |
| SCHEMBL4034371 | 0.80 | PPARA (0.69) | PPARAPPARGCYP4F2CYP4A11PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-B1 | Benzoxazole compound and pharmaceutical composition containing the compound | KOWA CO (JP) | 2011-09-21 | — | — | EP | disclosed |
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |