Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29722960 | 0.81 | ALDH1A1 (0.35) | KDM4EATMMAPK14 | |
| SCHEMBL775820 | 0.81 | ALDH1A1 (0.35) | KDM4EATMMAPK14 | |
| SCHEMBL11016102 | 0.80 | PDE7A (0.49) | KDM4ECYP1A2CYP2C19ALOX15HSD17B10 | |
| SCHEMBL10890165 | 0.80 | HSD17B10 (0.42) | CRHBPCRHR2HSD17B10PPARD | |
| SCHEMBL24377911 | 0.78 | HTT (0.31) | RAB9ASLC6A4 | |
| SCHEMBL1255217 | 0.73 | ATM (0.39) | KDM4EATML3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL28941715 | 0.73 | ATM (0.50) | KDM4EATML3MBTL1LDHAPLA2G1B | |
| SCHEMBL6602067 | 0.73 | KDM4E (0.35) | KDM4EATML3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL10930709 | 0.73 | MAPK1 (0.51) | CYP1A2PPARD | |
| SCHEMBL20220175 | 0.72 | GAA (0.34) | PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022084990-A1 | METHODS FOR THE PREPARATION OF PYRAZOLO[3,4-D]PYRIMIDIN-4-ONES AND INTERMEDIATES USED THEREIN | ADAMA MAKHTESHIM LTD. (IL) | 2022-04-28 | — | — | WO | disclosed |