Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29546618 | 1.00 | SLC6A4 (0.62) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL16610216 | 0.85 | SLC6A4 (0.62) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL7864995 | 0.82 | SLC6A4 (0.72) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL4670751 | 0.80 | SLC6A4 (0.81) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL30692838 | 0.78 | SLC6A4 (0.66) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL24377908 | 0.78 | SLC6A4 (0.42) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL24377909 | 0.78 | GABRP (0.56) | LMNAHTR6 | |
| SCHEMBL2065242 | 0.77 | SLC6A4 (0.67) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL3130981 | 0.77 | SLC6A4 (1.00) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL7859785 | 0.76 | SLC6A4 (0.72) | SLC6A4KDM4ELMNAPOLBHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116249526-A | TYK2 selective inhibitors and uses thereof | 南京药石科技股份有限公司 | 2023-06-09 | — | — | CN | disclosed |
| WO-2022083560-A1 | TYK2 SELECTIVE INHIBITOR AND USE THEREOF | 南京药石科技股份有限公司 | 2022-04-28 | — | — | WO | disclosed |