Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM4B | O94953 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27015063 | 0.79 | DYRK1A (0.48) | ECE1ALDH1A1GAARECQLKDM4E | |
| SCHEMBL27009169 | 0.79 | ECE1 (0.42) | ECE1ALDH1A1GAARECQLKDM4E | |
| SCHEMBL24359598 | 0.78 | GAA (0.52) | ECE1ALDH1A1GAARECQLKDM4E | |
| SCHEMBL18157906 | 0.76 | KMT2A (0.64) | KMT2AALDH1A1KDM4EKDM4AKDM4B | |
| SCHEMBL24378674 | 0.72 | PDE10A (0.50) | KMT2AALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL12605589 | 0.70 | ALDH1A1 (0.47) | ALDH1A1GAARECQLKDM4EPOLB | |
| SCHEMBL12970276 | 0.69 | ALDH1A1 (0.53) | ECE1KMT2AALDH1A1GAARECQL | |
| SCHEMBL15182828 | 0.68 | ALDH1A1 (0.51) | ECE1KMT2AALDH1A1GAARECQL | |
| SCHEMBL2053087 | 0.68 | MET (0.42) | KMT2AKEAP1PIK3CDPIP5K1CPIK3CA | |
| SCHEMBL14401137 | 0.68 | CDK4 (0.47) | KMT2AALDH1A1KDM4EMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022086993-A1 | NOVEL INHIBITORS OF PIKFYVE AND METHODS USING SAME | TME THERAPEUTICS LLC (US) | 2022-04-28 | — | — | WO | disclosed |