Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 7/20 | 0.56 |
| ▸ | HTR2C | P28335 | 7/20 | 0.44 |
| ▸ | HTR2B | P41595 | 7/20 | 0.44 |
| ▸ | HTR2A | P28223 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24379144 | 1.00 | CRBN (0.56) | CRBNHTR2CHTR2BHTR2AKMT2A | |
| SCHEMBL24379156 | 1.00 | CRBN (0.56) | CRBNHTR2CHTR2BHTR2AKMT2A | |
| SCHEMBL24379147 | 1.00 | CRBN (0.56) | CRBNHTR2CHTR2BHTR2AKMT2A | |
| SCHEMBL24379149 | 0.82 | CRBN (0.38) | CRBNDDB1 | |
| SCHEMBL20811718 | 0.81 | CRBN (0.76) | CRBNHTR2CHTR2BHTR2AKMT2A | |
| SCHEMBL24379143 | 0.80 | ADAM17 (0.41) | CRBNBRD4CREBBPDDB1 | |
| SCHEMBL24379421 | 0.79 | CRBN (0.53) | CRBNBRD4CREBBPALDH1A1CHRM2 | |
| SCHEMBL24379064 | 0.79 | CRBN (0.53) | CRBNBRD4CREBBPALDH1A1CHRM2 | |
| SCHEMBL20812351 | 0.79 | CRBN (0.53) | CRBNBRD4CREBBPALDH1A1CHRM2 | |
| SCHEMBL14511569 | 0.79 | CRBN (0.53) | CRBNBRD4CREBBPALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087125-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR PROTEIN | ARVINAS OPERATIONS, INC. (US) | 2022-04-28 | — | — | WO | disclosed |