SCHEMBL24379967

SCHEMBL24379967

O=C(OCC1OCC(OC(=O)c2ccccc2)C(OC(=O)c2ccccc2)C1OC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ BCHE P06276 5/20 0.48
▸ MEN1 O00255 1/20 0.47
▸ USP2 O75604 1/20 0.47
▸ POLB P06746 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ PTPN1 P18031 2/20 0.45
▸ ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18654234 1.00 BCHE (0.48) BCHEMEN1USP2POLBKMT2A
SCHEMBL21650368 1.00 BCHE (0.48) BCHEMEN1USP2POLBKMT2A
SCHEMBL20713679 1.00 BCHE (0.48) BCHEMEN1USP2POLBKMT2A
SCHEMBL22166492 1.00 BCHE (0.48) BCHEMEN1USP2POLBKMT2A
SCHEMBL21886718 0.96 BCHE (0.49) BCHEMEN1USP2POLBKMT2A
SCHEMBL14413573 0.96 BCHE (0.49) BCHEMEN1USP2POLBKMT2A
SCHEMBL19944547 0.96 BCHE (0.49) BCHEMEN1USP2POLBKMT2A
SCHEMBL23348434 0.96 BCHE (0.49) BCHEMEN1USP2POLBKMT2A
SCHEMBL14208566 0.96 BCHE (0.49) BCHEMEN1USP2POLBKMT2A
SCHEMBL16749107 0.96 BCHE (0.49) BCHEMEN1USP2POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220177885-A1 ENDOSOMAL CLEAVABLE LINKERS ALNYLAM PHARMACEUTICALS, INC. (US) 2022-06-09 — — US disclosed
US-11319338-B2 Timosaponin compounds GOLDPORP PHARMA LIMITED (HK) 2022-05-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11319338-B2 Timosaponin compounds APP, IAPP, BACE1 BCHE 101/4885MEN1 1058/4885USP2 4673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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