Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 7/20 | 0.61 |
| ▸ | EGFR | P00533 | 3/20 | 0.56 |
| ▸ | JAK3 | P52333 | 12/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | ITK | Q08881 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24380783 | 0.90 | BTK (0.59) | BTKEGFRJAK3JAK1 | |
| SCHEMBL18877721 | 0.84 | BTK (0.86) | BTKEGFRJAK3JAK1ITK | |
| SCHEMBL14228143 | 0.84 | BTK (0.86) | BTKEGFRJAK3JAK1ITK | |
| SCHEMBL19097822 | 0.81 | BTK (0.71) | BTKEGFRJAK3JAK1 | |
| SCHEMBL21386777 | 0.79 | BTK (0.75) | BTKEGFRJAK3JAK1 | |
| SCHEMBL17816357 | 0.79 | BTK (0.77) | BTKEGFRITK | |
| SCHEMBL21386748 | 0.79 | BTK (0.74) | BTKEGFRJAK3JAK1ITK | |
| SCHEMBL18518588 | 0.79 | BTK (0.60) | BTKEGFRJAK3JAK1 | |
| SCHEMBL18618516 | 0.78 | BTK (0.67) | BTKEGFRJAK3JAK1 | |
| SCHEMBL23735023 | 0.78 | BTK (0.61) | BTKEGFRJAK3JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3643716-B1 | HETEROARYL COMPOUND HAVING PHARMACEUTICAL ACTIVITY | SHANGHAI DUDE MEDICAL TECH CO LTD (CN) | 2022-05-04 | — | — | EP | disclosed |