SCHEMBL24390176

SCHEMBL24390176

CCC(CC)COC(=O)/C(C#N)=C/C=C1\Oc2ccccc2N1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 9/20 0.43
▸ MEN1 O00255 9/20 0.43
▸ KMT2A Q03164 9/20 0.43
▸ ALDH1A1 P00352 6/20 0.43
▸ MAPK1 P28482 2/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ RAB9A P51151 6/20 0.40
▸ GAA P10253 4/20 0.40
▸ NPC1 O15118 4/20 0.40
▸ USP2 O75604 3/20 0.40
▸ SMN1; SMN2 Q16637 3/20 0.40
▸ NPSR1 Q6W5P4 3/20 0.40
▸ FNTA P49354 4/20 0.39
▸ FNTB P49356 4/20 0.39
▸ LMNA P02545 4/20 0.39
▸ CYP3A4 P08684 2/20 0.36
▸ CYP2C9 P11712 2/20 0.36
▸ CYP2C19 P33261 2/20 0.36
▸ POLB P06746 2/20 0.36
▸ CYP2D6 P10635 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24390210 0.89 MAPT (0.54) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL24390163 0.82 MAPT (0.41) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL24390172 0.81 MAPT (0.39) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL24390168 0.81 MEN1 (0.41) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL24390254 0.79 MAOB (0.45) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL24390236 0.79 KMT2A (0.43) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL24390191 0.78 FNTA (0.49) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL24390211 0.77 MAPT (0.61) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL24390180 0.76 MAPT (0.50) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL24390234 0.73 MEN1 (0.51) MAPTMEN1KMT2AALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220137260-A1 POLYMERIZABLE COMPOSITION, COMPOUND, POLYMER, RESIN COMPOSITION, ULTRAVIOLET CUT FILM, AND LAMINATE FUJIFILM CORPORATION (JP) 2022-05-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220137260-A1 POLYMERIZABLE COMPOSITION, COMPOUND, POLYMER, RESIN COMPOSITION, ULTRAVIOLET CUT FILM, AND LAMINATE RER1, C5, RAD51 MAPT 1441/4885MEN1 1611/4885KMT2A 2985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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